You Searched For: tert-Butyl+(5-bromopyrazin-2-yl)carbamate


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Supplier: Bachem Americas
Description: Sequence: Fmoc-β-(1-piperazinyl)-Ala(Boc)-OH

Supplier: Adipogen
Description: CGI1746 was identified as a selective and potent ATP-competitive BTK inhibitor with an IC(50) of 1.9nM. It is specific for BTK, with around 1000-fold selectivity over Tec and Src family kinases.

Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 042458-5G , MDL Number: MFCD04974254

Supplier: AMBEED, INC
Description: Butyl carbamate 98%

Supplier: Adipogen
Description: Quizartinib (AC220) is a second-generation FLT3 inhibitor that has shown promising activity in AML in Phase II clinical trials. It inhibits mutant and wild-type FLT3 in vivo at 0.1 and 0.5µM, respectively, and has shown favorable activity and tolerability in phase I and II trials in acute myeloid leukemia, with QT prolongation as the dose-limiting toxicity. Recently, AC220 has also been shown to be an effective inhibitor of ATP-binding cassette (ABC) proteins ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein). Quizartinib inhibited transport of fluorescent ABCG2 and ABCB1 substrates in ABCG2- and ABCB1-overexpressing cells in a concentration-dependent manner, from 0.1 to 5µM and from 0.5 to 10µM, respectively, and inhibited-IAAP photolabeling of ABCG2 and ABCB1 with IC(50) values of 0.07 and 3.3µM, respectively.

Supplier: Adipogen
Description: (+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. In binding assays, (+)-JQ1 binds competitive with acetyl lysine to BRD4 bromodomain 1 (Kd=50nM) and and BRD4 bromodomain 2 (Kd=90 nM). May be a useful chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. (+)-JQ1 exhibited strong dose- and time-dependent inhibition of BRDT, a bromodomain-containing protein highly enriched in testis. BRDT is involved in chromatin remodeling and is essential for healthy sperm development. (+)-JQ1 appears to block that function and causes a decrease in sperm viability, being examined as a potential male contraceptive. Inhibitor of inflammation and bone destruction.

Supplier: TCI America
Description: CAS Number: 592-35-8 MDL Number: MFCD00007967 Molecular Formula: C5H11NO2 Molecular Weight: 117.15 Purity/Analysis Method: <gt/>98.0% (GC) Form: Crystal Boiling point (°C): 204 Melting point (°C): 54 Flash Point (°C): 108

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Supplier: Adipogen
Description: Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon http://www.adipogen.com/ag-cr1-0154/adiporon.html . Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.

Supplier: APOLLO SCIENTIFIC
Description: (2-Aminoethyl)benzyl carbamic acid-tert-butylester

Supplier: AMBEED, INC
Description: Ethyl (4-oxo-4-(phenethylamino)butyl)carbamate, Purity: 98%, CAS Number: 1477949-42-0, Appearance: White to Yellow Solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 1mg

Catalog Number: (BDH1139-4LG)
Supplier: BDH
Description: Meets ACS specifications for general use.

Catalog Number: (BDH67005.400)
Supplier: VWR International
Description: BDH* Methyl t-Butyl Ether, Chemical Formula: (CH3)3COCH3, Melting Point:, Boiling Point:, Flash Point: -32 deg C, Formula Weight:, CAS Number: 1634-04-4, Grade: HPLC/Spectro, HiPerSolv CHROMANORM, Class: F, Size: 4L

Supplier: AMBEED, INC
Description: (R)-Benzyl (2-oxotetrahydrofuran-3-yl)carbamate 98+%

Catalog Number: (102900-288)
Supplier: Matrix Scientific

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Supplier: Matrix Scientific
Description: Ethyl N-[(5-Methylpyridin-2-Yl)Carbamothioyl]Carbamate, MF=C10H13N3O2S, MW=239.30, CAS=37890-99-6, 500MG

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Supplier: Matrix Scientific
Description: Matrix Scientific Part Number: 058675-1G , MDL Number: MFCD09030045

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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