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Catalog Number: (75932-818)
Supplier: Rockland Immunochemical
Description: Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.


Catalog Number: (103635-560)
Supplier: Sino Biological
Description: Produced in rabbits immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met 1-Thr 426). TEM7 / PLXDC1 specific IgG was purified by Human TEM7 / PLXDC1 affinity chromatography.


Catalog Number: (103635-536)
Supplier: Sino Biological
Description: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met1-Thr426). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.


Catalog Number: (103635-554)
Supplier: Sino Biological
Description: Produced in rabbits immunized with purified, recombinant Human TEM7 / PLXDC1 (rh PLXDC1; Catalog#11736-H08H; AAH36059.1; Met1-Thr426). Total IgG was purified by Protein A affinity chromatography.


Catalog Number: (75932-820)
Supplier: Rockland Immunochemical
Description: Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.


Catalog Number: (103635-552)
Supplier: Sino Biological
Description: This antibody was obtained from a rabbit immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met 1-Thr 426).


Catalog Number: (103608-610)
Supplier: Sino Biological
Description: Produced in rabbits immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met1-Thr426). TEM7 / PLXDC1 specific IgG was purified by Human TEM7 / PLXDC1 affinity chromatography.


Catalog Number: (103635-544)
Supplier: Sino Biological
Description: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met 1-Thr 426). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.


Catalog Number: (103635-548)
Supplier: Sino Biological
Description: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TEM7/PLXDC1 (rh TEM7/PLXDC1; Catalog#11736-H08H; AAH36059.1; Met1-Thr426). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.


Catalog Number: (103635-540)
Supplier: Sino Biological
Description: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met1-Thr426). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.


Catalog Number: (103615-852)
Supplier: Sino Biological
Description: A DNA sequence encoding the human PLXDC1 (AAH36059.1) extracellular domain (Met 1-Thr 426) was expressed, with a polyhistidine tag at the C-terminus


Supplier: Bon Opus Biosciences
Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Catalog Number: (77208-380)
Supplier: ANTIBODIES.COM LLC
Description: Human TEM7 ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human TEM7 in serum, plasma, and other biological fluids.


Catalog Number: (75789-634)
Supplier: Prosci
Description: Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).


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