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Catalog Number: (58954-025)
Supplier: Glas-Col
Description: Heavy duty lab stand made to last with stainless steel mast and cast iron base.

Small Business Enterprise


Catalog Number: (10368-398)
Supplier: Bioss
Description: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.


Catalog Number: (95027-218)
Supplier: Diagnostic Biosystems
Description: This kit stains reticulum fibers in paraffin tissue sections


Supplier: Marlin Steel Wire Products
Description: A custom hand hygiene solution for ensuring sanitation in any facility. The plain steel, black-coated stand is designed to work with different dispenser models across various brands, as well as Marlin’s no-touch sanitizer dispenser.

Catalog Number: (89416-642)
Supplier: Prosci
Description: SATB1 Antibody: Human special AT-rich sequence-binding protein-1 (SATB1) is a nuclear matrix/scaffold-associated region DNA-binding protein, predominantly expressed in the thymus and pre-B cells. Like its homolog SATB2, SATB1 selectively binds double-stranded, special AT-rich DNA sequences in which one strand exclusively consists of well-mixed A, T, and C nucleotides. SATB1 contains a dimerization domain that shares similarity with the PDZ motif, identified as an indispensable element for high-affinity binding of SATB1 to DNA. SATB1 constitutes a functional nuclear architecture that has a 'cage-like' protein distribution surrounding heterochromatin and regulates gene expression through chromatin remodeling/HDAC (histone deacetylase complex) and transcription factors recruitment. SATB1 functions as a 'genome organizer' essential for proper T-cell development. Recent studies show that SATB1 is necessary for breast cancer cells to become metastatic, and when ectopically expressed in non-metastatic cells, can induce invasive activity in vivo. At least two isoforms of SATB1 are known to exist.


Supplier: Plas-Labs
Description: These nitrogen cabinets are designed to protect, store, or assist in transporting critical materials such as research specimens or moisture-sensitive devices that require a dry, contaminant-free environment

Small Business Enterprise

Catalog Number: (470234-848)
Supplier: GEOGLOBAL PARTNERS
Description: Improve Your biOrb® Aquaria.


Catalog Number: (77663-032)
Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: Boom clamp stand without focus mount.

New Product


Catalog Number: (77707-284)
Supplier: AFG BIOSCIENCE LLC
Description: WB:1:500-1:3000

New Product


Catalog Number: (102971-094)
Supplier: Li-Cor
Description: CellTag 700 Stain is a near-infrared fluorescent, non-specific cell stain that provides accurate normalization to cell number for In-Cell Western™ Assay applications.


Catalog Number: (470328-990)
Supplier: OMNIMED INCORPORATED SE
Description: Omnimed® beam stands provide a solution to securely transport instruments or equipment.


Catalog Number: (470224-996)
Supplier: American 3B Scientific
Description: Trainees and students in midwifery and obstetrics can practice correctly assessing the progress of the birth by palpating, using the birth stages trainer.


Catalog Number: (100504-752)
Supplier: Electron Microscopy Sciences
Description: Leukocyte Alkaline Phosphatase Phosphatase stain.

Minority or Woman-Owned Business Enterprise


Supplier: Scientific Materials
Description: Jumbo Stacking Cabinets are constructed of 2.5 cm (1") thick, multi-ply, exterior-grade plywood and finished with easily identified, chemical-resistant, yellow or blue epoxy paint.

Supplier: Janitorial Supplies
Description: Contoured seat and back for comfort

Supplier: IBI Scientific
Description: For Rollers Made Of 3/8 Inch Acrylic With Clear Anodized Aluminum 1 Inch Diameter Legs - 10 Inch High

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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