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Supplier: AMBEED, INC
Description: Ethyl 3-butenoate ≥98% stabilized

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Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: Dichloromethane 99.8% stabilized for spectroscopy

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Supplier: Akro-Mils
Description: Akro-Tubs are heavy-duty, industrial-grade nesting tubs that are ideal for industrial and food applications.

Catalog Number: (76068-972)
Supplier: Prosci
Description: SNTB2 Polyclonal Antibody, Host: Rabbit, Reactivity: Human, Isotype: Ig, Immunogen: KLH conjugated synthetic peptide between 217-245 amino acid from the Central region Human SNTB2, Synonym: SNTL, SNTB2, D16S2531E, SNT2B2,


Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: 2-Hydroxyethyl macrylate 99+% stabilized

Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: Chloroform 99+% stabilized for analysis

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Catalog Number: (77987-206)
Supplier: LGC STANDARDS
Description: Iodoethane (Stabilized with Copper), TRC, LGC Standards

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Catalog Number: (60941-176)
Supplier: Abgent
Description: Primary Rabbit Anti-CLLD8/SETDB2 (Center C195) Reacts with Human


Catalog Number: (76063-684)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000


Catalog Number: (76750-568)
Supplier: Prosci
Description: Anti-SKAP2 Rabbit Polyclonal Antibody


Catalog Number: (76760-852)
Supplier: Prosci
Description: Anti-SF3B2 Rabbit Polyclonal Antibody


Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: The MM-6 micropositioner is light weight, accurate, compact device designed to eliminate many research and design problems, especially in the case of space limitations. Hardened steel precision pre-loaded ball bearing slides and high resolution thumbscrew movement assure smooth motion, precision, and excellent load bearing capacity.

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Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: (Iodomethyl)cyclopentane 98% stabilized

Catalog Number: (76008-890)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100


Supplier: AMBEED, INC
Description: 9-Decen-1-ol 97% stabilized

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Catalog Number: (10372-564)
Supplier: Bioss
Description: Smad2 is a 58 kDa member of a family of proteins involved in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor-regulated Smad's, activin/TGF alpha receptor-regulated (Smad2 and 3) or BMP receptor regulated (Smad1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smad's; and the inhibitory Smad's, (Smad6 and Smad7). Smad2 consists of two highly conserved domains, the N terminal Mad homology (MH1) and the C-terminal Mad homology 2 (MH2) domains. The MH1 domain binds DNA and regulates nuclear import and transcription while the MH2 domain conserved among all the Smad's regulates Smad2 oligomerization and binding to cytoplasmic adaptors and transcription factors. Activated Smad2 associates with Smad4 and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. This translocation of Smad2 (as well as Smad3) into the nucleus is a central event in TGF beta signaling. Phosphorylation of threonine 8 in the calmodulin binding region of the MH1 domain by extracellular signal regulated kinase 1(ERK 1) enhances Smad2 transcriptional activity, which is negatively regulated by calmodulin. The regulation of Smad2 phosphorylation on threonine 8 by ERK 1 and calmodulin is critical for Smad2 mediated signaling.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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