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Catalog Number: (10094-116)
Supplier: Proteintech
Description: SAFB2, also named as Scaffold attachment factor B2 or KIAA0138, is a 953 amino acid protein, which contains one SAP domain and one RRM (RNA recognition motif) domain. SAFB2 expressed at high levels in the CNS and at low levels in the liver. It also is expressed in a wide number of breast cancer cell lines. SAFB2 binds to scaffold/matrix attachment region (S/MAR) DNA and can function as an estrogen receptor corepressor and can also inhibit cell proliferation.


Catalog Number: (102205-272)
Supplier: Novus Biologicals
Description: The SPSB2 Antibody from Novus Biologicals is a rabbit polyclonal antibody to SPSB2. This antibody reacts with human, rhesus macaque. The SPSB2 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry.


Catalog Number: (102104-664)
Supplier: Novus Biologicals
Description: The SETDB2 Antibody from Novus Biologicals is a goat polyclonal antibody to SETDB2. This antibody reacts with human. The SETDB2 Antibody has been validated for the following applications: Western Blot, Immunocytochemistry / Immunofluorescence, Peptide ELISA.


Catalog Number: (10087-916)
Supplier: Proteintech
Description: Anti-GSTA2 Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-222 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower


Catalog Number: (10732-312)
Supplier: Abnova
Description: Goat polyclonal antibody raised against synthetic peptide of SATB1.


Catalog Number: (10369-698)
Supplier: Bioss
Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.


Catalog Number: (10116-708)
Supplier: Prosci
Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: SETDB2 antibody was raised against a 13 amino acid synthetic peptide near the N-Terminus of SETDB2; Application: ELISA, Western Blot


Catalog Number: (10094-664)
Supplier: Proteintech
Description: SKAP2 (src kinase associated phosphoprotein 2), also named PRAP, contains PH domain and SH3 domain. It is localized in cytoplasm and was expressed in ubiquitously in various tissues including lung, skeletal muscle, and spleen, but not detectable in thymus and T cell lymphoma cells. SKAP2 may negatively regulate alpha-synuclein phosphorylation following cell stress. SKAP2 may be involved in B-cell and macrophage adhesion processes by coupling the B-cell receptor (BCR) to integrin activation.


Catalog Number: (10162-062)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to CTAG2


Catalog Number: (10116-672)
Supplier: Prosci
Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: SCAP2 antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of SCAP2; Application: ELISA, Western Blot


Catalog Number: (10667-282)
Supplier: Bioss
Description: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.


Catalog Number: (102711-516)
Supplier: Novus Biologicals
Description: The SETDB2 Antibody from Novus Biologicals is a rabbit polyclonal antibody to SETDB2. This antibody reacts with human. The SETDB2 Antibody has been validated for the following applications: Western Blot, Immunocytochemistry / Immunofluorescence, Immunoprecipitation.


Catalog Number: (10371-178)
Supplier: Bioss
Description: Siah2 is a E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targets. Siah2 triggers the ubiquitin-mediated degradation of many proteins, including transcription regulators (e.g. POU2AF1, PML, NCOR1), cell surface receptors (e.g. DCC), antiapoptotic proteins (e.g. BAG1), and proteins involved in synaptic vesicle function in neurons (e.g. SYP). Siah2 has some overlapping function with SIAH1 but is able to trigger the ubiquitin-mediated degradation of TRAF2, whereas SIAH1 can not.


Catalog Number: (102166-640)
Supplier: Novus Biologicals
Description: The SNTB2 Antibody from Novus Biologicals is a rabbit polyclonal antibody to SNTB2. This antibody reacts with human. The SNTB2 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (10369-700)
Supplier: Bioss
Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.


Catalog Number: (10094-154)
Supplier: Proteintech
Description: Epigenetic modifications and dynamic changes in chromatin organization by organizer proteins have recently been shown to play an instrumental role in regulating cancer-promoting genes. Special AT-rich binding protein (SATB1) is a unique type of global regulator that integrates higher-order chromatin organization -withregulation of gene expression. SATB1 is a T cell-enriched transcription factor and a chromatin organizer essential for controlling genes that participate in T-cell development and activation. It regulates gene expression by periodically anchoring matrix attachment regions to the nuclear matrix and directly recruiting chromatin-modifying factors. Depending on its posttranslational modifications, SATB1 activates or represses multiple genes.Its expression is regulated by interleukin-4 (IL4) during T helper-2(Th2) cell differentiation.


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