You Searched For: stab1

Catalog Number: (102212-136)

Supplier: Novus Biologicals

Description: The Smad1 [p Ser206] Antibody from Novus Biologicals is a rabbit polyclonal antibody to Smad1. This antibody reacts with human, mouse, rat, canine. The Smad1 [p Ser206] Antibody has been validated for the following applications: Western Blot, ELISA.

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Catalog Number: (10365-974)

Supplier: Bioss

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].

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Catalog Number: (10259-906)

Supplier: Bioss

Description: The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].

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Catalog Number: (77800-250)

Supplier: AFG BIOSCIENCE LLC

Description: 24899

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Catalog Number: (89399-186)

Supplier: Abgent

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Catalog Number: (60941-170)

Supplier: Abgent

Description: Purified Rabbit Polyclonal Antibody (Pab). This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SETDB1. Specificity: H. Concentration: 0.25 mg/ml. Size: 0.1 mg.

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Catalog Number: (77851-961)

Supplier: AFG BIOSCIENCE LLC

Description: Anti-BTAF1 Rabbit Recombinant Polyclonal Antibody

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Catalog Number: (10261-094)

Supplier: Bioss

Description: SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.

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Catalog Number: (89378-360)

Supplier: Abgent

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Catalog Number: (77739-128)

Supplier: AFG BIOSCIENCE LLC

Description: 13917

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Catalog Number: (89396-754)

Supplier: Abgent

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Catalog Number: (89390-118)

Supplier: Abgent

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Catalog Number: (10365-990)

Supplier: Bioss

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].

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Catalog Number: (10365-996)

Supplier: Bioss

Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].

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Catalog Number: (89385-470)

Supplier: Abgent

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Catalog Number: (89291-694)

Supplier: Genetex

Description: Mouse Monoclonal antibody [5H6A12] to SETDB1

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