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Catalog Number: (77798-673)
Supplier: AFG BIOSCIENCE LLC
Description: 23928

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Catalog Number: (80079-172)
Supplier: Binder
Description: Accessories for Standard-Incubators with Natural Convection, Avantgarde.line BD Series, Binder

Product available on GSA Advantage®


Catalog Number: (ABCA_AB244470-100U)
Supplier: ABCAM INC.
Description: Anti-STAM1 Rabbit Polyclonal Antibody

New Product


Catalog Number: (89387-202)
Supplier: Abgent


Catalog Number: (77700-629)
Supplier: AFG BIOSCIENCE LLC
Description: WB:1:500-1:2000, IHC:1:100-1:300, IP:2-5ug, ELISA:1:10000

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Catalog Number: (10491-846)
Supplier: Bioss
Description: Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-å and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3∫ appears to be activated by both while Stat3å is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.


Catalog Number: (76851-508)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to STAT1 for WB and IHC with samples derived from Human, Mouse and Rat.


Catalog Number: (10491-858)
Supplier: Bioss
Description: Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-å and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3∫ appears to be activated by both while Stat3å is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.


Catalog Number: (76738-558)
Supplier: ANTIBODIES.COM LLC
Description: Human STAT1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human STAT1 in serum, plasma, tissue homogenates, and other biological fluids.


Catalog Number: (77691-127)
Supplier: AFG BIOSCIENCE LLC
Description: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

New Product


Catalog Number: (ABCA_AB99415-100UL)
Supplier: ABCAM INC.
Description: Anti-STAT1 Rabbit Polyclonal Antibody

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Catalog Number: (76083-942)
Supplier: Bioss
Description: Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis.


Catalog Number: (76729-826)
Supplier: ANTIBODIES.COM LLC
Description: Mouse STUB1/CHIP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse STUB1/CHIP in serum, plasma, tissue homogenates, and other biological fluids.


Catalog Number: (77070-922)
Supplier: ANTIBODIES.COM LLC
Description: Goat polyclonal antibody to STUB1 for ELISA and WB with samples derived from Human.


Catalog Number: (103338-574)
Supplier: Novus Biologicals
Description: The CHIP / STUB1 Antibody from Novus Biologicals is a mouse polyclonal antibody to CHIP / STUB1. This antibody reacts with human, mouse, rat. The CHIP / STUB1 Antibody has been validated for the following applications: Western Blot, ELISA.


Catalog Number: (77077-944)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to STAT1 for WB and ELISA with samples derived from Human.


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