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Catalog Number: (MFLX97411-88)
Supplier: VESTA INTERMEDIATE FUNDING INC
Description: Up to five times longer life and lower spallation provides enhanced consistency over time.


Supplier: VWR International
Description: Corrosion-resistant, stainless steel horizontal racks feature handles for easy transport.

Catalog Number: (10394-968)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.


Catalog Number: (10388-024)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.


Catalog Number: (MFLX07596-20)
Supplier: MASTERFLEX LLC
Description: Virtually eliminate pulsation in output flow.


Catalog Number: (470149-302)
Supplier: VWR International
Description: Flasks feature a permanent graduation line and large marking area, and necks are tooled to fit the included glass stoppers.

Supplier: Thermo Scientific
Description: This wireless monitoring solution for laboratory equipment safeguards the integrity of precious samples by continuously monitoring critical parameters and securely logging data to provide unprecedented peace-of-mind. Featuring audit trail traceability, this solution assists with conformance to 21 CFR Part 11, and other strenuous regulatory requirements for labs operating in regulated industries. System features software, modules, repeaters, receivers, and a 915 Mhz frequency (North America).

Product available on GSA Advantage®

Catalog Number: (14216-208)
Supplier: VWR International
Description: These heavy-duty clamps support overhead mixers and homogenizers.

Product available on GSA Advantage®


Supplier: MASTERFLEX LLC
Description: Versatile pumps for process applications – with an intuitive touch-screen interface and advanced connectivity.

UL Listed cUL Listed CE Compliant 2 year warranty

Supplier: MASTERFLEX LLC
Description: Built for bioprocess applications - designed for ease of use and process flexibility.

Supplier: VWR International
Description: Includes an extra wire frame shelf made to fit VWR® Standard series laboratory refrigerators. (Includes SLV models).

Supplier: MASTERFLEX LLC
Description: Easy-to-use drives offer precise speed control and digital display of rpm—NEMA 4X housings stand up to process and washdown applications.

ETL listed ETL Canada listed ISO9001 IP66 washdown CE Compliant 2 year warranty

Supplier: MCR Safety
Description: Heavy select gray side-split leather provides outstanding protection from heat, sparks, slag, and cuts.

Supplier: MASTERFLEX LLC
Description: Versatile variable-speed drive with a wide flow range and simple controls.

CE Compliant 2 year warranty

Supplier: VWR International
Description: Disposable caps are for 12 x 75 mm and 13 x 100 mm culture tubes.
Supplier: MASTERFLEX LLC
Description: Simplify your dispensing.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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