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Description: The opioid receptors delta (DOP, OP1), kappa (KOP, OP2), and mu (MOP, OP3) are members of the seven-transmembrane domain-containing receptor family of G-protein coupled receptors, sharing nearly 60% identity, but varying greatly in the extracellular N-terminus region of the receptors. The delta, kappa and mu-receptors serve as functional receptors for endogenous enkephalin, dynorphin, and beta-endorphin peptide ligands, respectively, mediating their signal via coupling to Gi/o alpha subunits to inhibit adenylyl cyclases and calcium conductance (N- and L-type channels), and to stimulate MAPK activation and potassium conductance. Delta-opioid receptors are highly expressed in the olfactory bulb, neocortex, caudate putamen and nucleus accumbens, with peripheral expression in the gastro-intestinal tract and vas deferens. Delta-opioid receptors function to inhibit neurotransmitter release resulting in a variety of biological effects including analgesia, motor integration, gastro-intestinal motility, olfaction,

Catalog Number: 89141-462

Supplier: Enzo Life Sciences

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Description: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 81 kDa in size corresponding to Ankrd26 by western blotting.

Catalog Number: RL600-401-917

Supplier: Rockland Immunochemical

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Description: This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1) is a Protein Coding gene. This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. ASAP1 may function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity) and plays a role in ciliogenesis. Anti-ASAP1 is useful for researchers interested in GTPase activities and EGFR1 Signaling Pathway.

Catalog Number: 76262-750

Supplier: Rockland Immunochemical

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Description: Monkey IgG Alkaline Phosphatase Conjugate

Catalog Number: RL017-0502

Supplier: Rockland Immunochemical

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Description: Llama IgG1 isotype control Fluorescein Conjugate

Catalog Number: 76221-914

Supplier: Rockland Immunochemical

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Description: Anti-Maltose Phosphorylase has a working dilution of 1:2,000 to 1:10,000 of the reconstitution concentration is suggested for this product.

Catalog Number: RL200-103-230S

Supplier: Rockland Immunochemical

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Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

Catalog Number: RL016-0304

Supplier: Rockland Immunochemical

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Description: ImmunoReagents’ Biotinylated antibody conjugates are widely used due to their ability to enhance antibody signal in most immunoassays. Biotinylated secondary antibodies are used in most immunoassay formats (i.e., ELISA, Immunohistochemistry (IHC), and Western blotting). While Biotinylated antibodies by themselves do not produce a signal that can be visualized, biotin has a high affinity and specificity to Streptavidin/Avidin. Using ImmunoReagents’ streptavidin conjugates with biotinylated antibodies results in signal amplification.

Catalog Number: 10150-172

Supplier: Immunoreagents

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Description: Anti-Pyranose Oxidase (E.Coli) (Goat) Antibody Biotin Conjugated - Anti-Pyranose Oxidase Antibody Has Been Assayed Against 1 Ug Of Pyranose Oxidase In A Standard Capture ELISA Using Peroxidase Conjugated Streptavidin And Abts As A Substrate For 30 Minutes.

Catalog Number: RL200106235S

Supplier: Rockland Immunochemical

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Description: ERK2 antibodies detect the ERK2 isoform. Mitogen activated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Catalog Number: 76235-050

Supplier: Rockland Immunochemical

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Description: Anti-Mouse IgG DyLight549 Antibody generated in rabbit detects reactivity to Mouse IgG1, IgG2a, IgG2b and IgG3. Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75% of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsinization for phagocytosis. The whole IgG molecule possesses both the F(c) region, recognized by high-affinity Fc receptor proteins, as well as the F(ab) region possessing the epitope-recognition site. IgG1, IgG2a, IgG2b and IgG3 chains of the antibody molecule are present. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment composition.

Catalog Number: 76225-984

Supplier: Rockland Immunochemical

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Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

Catalog Number: RL006-0203

Supplier: Rockland Immunochemical

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Description: MEK1 antibodies detect the MEK1 isoform. Mitogen-activated protein kinase kinase 1, also known as MKK or MEK, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. The MEK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Catalog Number: 76263-060

Supplier: Rockland Immunochemical

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Description: ERK2 antibodies detect the ERK2 isoform. Mitogen activiated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Catalog Number: 76262-978

Supplier: Rockland Immunochemical

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Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

Catalog Number: RL016-0204

Supplier: Rockland Immunochemical

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89155-266

Supplier: Enzo Life Sciences

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