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Catalog Number: (76000-914)
Supplier: KD Scientific
Description: The Gemini 88 Plus Dual Rate Syringe Pump is really two syringe pumps in one by providing two independent pumping channels linked through hardware and an intuitive 7” touch screen interface. This dual rate syringe pump can infuse simultaneously at different rates, or infuse with one syringe and withdraw with the other. When combined with a valve box, it provides the continuous delivery of a peristaltic pump with the accuracy and low flow rates of a syringe pump.


Catalog Number: (10270-620)
Supplier: Bioss
Description: Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).


Catalog Number: (95056-118)
Supplier: GE Healthcare - Life Sciences
Description: HiTrap ANX (high sub) FF is prepacked with ANX (high sub) Sepharose Fast Flow, and is a weak anion exchanger for small scale purification of higher molecular weight protein as well as screening of binding and elutions conditions

Catalog Number: (82006-866)
Supplier: Labconco
Description: Safely transports heavy instruments and bulky equipment.

Product available on GSA Advantage®


Catalog Number: (89141-478)
Supplier: Enzo Life Sciences
Description: The octapeptide circulatory hormone Angiotensin II is a critical regulator of cardiovascular homeostasis formed in blood, with dual function in tissues of the brain, kidney, heart, and vasculature as an autocrine/paracrine growth hormone. The actions of angiotensin II are mediated by type one (AT1) and type two (AT2) angiotensin II receptors, members of the seven-transmembrane Gprotein coupled receptor (GPCR) family. AT1 receptors couple predominantly with Gq/11 alpha subunits, and signal through phospholipases C, D, and A2, inositol phosphates, and calcium channels, as well as a variety of serine/threonine and tyrosine kinases. AT1 expression is greatest in vascular smooth muscle, liver, kidney, adrenal cortex, brain, and lung, and is primarily responsible for the physiological effects of angiotensin II, including regulation of arterial blood pressure, electrolyte and water balance, thirst, hormone secretion, and renal function. The AT2 receptor displays approximately 30% identity to the AT1 receptor, and is highly expressed during embryonic development. AT2 expression in adult tissue is limited to the adrenal medulla, brain, and reproductive tissues, but is upregulated in injured tissue following myocardial infarction, vascular injury, and wound healing. AT2 receptor signaling is not dependent on G-protein coupling or receptor phosphorylation, although coupling to Gia2 and Gia3 alpha subunits occurs in some tissues. AT2 activation can stimulate tyrosine and serine/threonine phosphatases through activation of nitric oxide and cGMP, and appears to counteract the stimulatory effects of AT1 receptor and growth factor receptor signaling.


Catalog Number: (10270-634)
Supplier: Bioss
Description: Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).


Catalog Number: (76031-626)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Aqua–Pure™ whole house large diameter stainless steel water filter housing SS4 EPE–316L together with many filter cartridges, filters all incoming water throughout the entire home or light commercial application. This housing can be used for both chlorinated (municipal) and non–chlorinated (well water) systems.


Catalog Number: (76028-666)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge Kit, Model CARTPAK DP290 provides consistent high quality water by reducing particulate*, chlorine taste and odor, scale*, cyst**, and bacteria1. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs. Includes two (2) HF90 cartridges and one (1) HF8–S cartridge.


Catalog Number: (10305-520)
Supplier: Bioss
Description: G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent manner. Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation. Plays a role in blood glucose homeostasis contributing to the insulin secretion response by pancreatic beta cells. Triggers mitochondrial apoptosis during pachytene spermatocyte differentiation. Stimulates uterine epithelial cell proliferation. Enhances uterine contractility in response to oxytocin. Contributes to thymic atrophy by inducing apoptosis. Attenuates TNF-mediated endothelial expression of leukocyte adhesion molecules. Promotes neuritogenesis in developing hippocampal neurons. Plays a role in acute neuroprotection against NMDA-induced excitotoxic neuronal death. Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons. Inhibits early osteoblast proliferation at growth plate during skeletal development. Inhibits mature adipocyte differentiation and lipid accumulation. Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells.


Catalog Number: (76030-684)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Under Sink Reverse Osmosis Water Filter System 3MRO301 is a multi-stage reverse osmosis water filter system that is NSF certified to reduce particulate, chlorine taste and odor, arsenic, barium, cadmium, chromium (both Hexavalent and Trivalent), copper, parasitic protozoan cysts, fluoride, lead, radium, selenium, TDS and turbidity.


Catalog Number: (76028-680)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series System for Cold Beverage Applications, Model BEV190 provides consistent high quality water by reducing particulate*, chlorine taste and odor, cyst**, and bacteria1. The Sanitary Quick Change (SQC) design allows for easy cartridge change-outs. For use in cold beverage applications.


Catalog Number: (10270-640)
Supplier: Bioss
Description: Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).


Catalog Number: (76028-672)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge Kit, Model CARTPAK DP260 provides consistent high quality water by reducing particulate*, chlorine taste and odor, scale*, cyst**, and bacteria1. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs. Package includes two (2) HF60 cartridges and one (1) HF8–S cartridge.


Catalog Number: (36434-434)
Supplier: ACCUFORM MANUFACTURING, INC
Description: Displays biohazard symbol and word.


Catalog Number: (76028-682)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series System for Cold Beverage Applications, Model BEV195 provides consistent quality water by reducing particulate* and chlorine taste and odor. The Sanitary Quick Change (SQC) encapsulated cartridge design allows for fast and easy cartridge change-outs without the need for a filter wrench. Designed for use in carbonator and cold beverage dispenser applications.


Catalog Number: (76030-316)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge Kit, Model CARTPAK DP390 provides consistent high quality water by reducing particulate*, chlorine taste and odor, scale*, cyst**, and bacteria. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs. Includes three (3) HF90 cartridges and one (1) HF8–S cartridge.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
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* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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