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Supplier: AmTab Manufacturing Corporation
Description: All-welded utility tables are used every day throughout the world in multi-purpose environments including schools, offices, and retail stores. Our high-quality state-of-the-art tables are safe, durable, easy to operate, and a great long-term value. Tables are perfect for heavy-use and heavy-turn settings providing years of trusted service.

Environmentally Preferable

Catalog Number: (77436-806)
Supplier: Bioss
Description: Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits. The alpha subunits consist of CNG1-3 and form functional cation channels by themselves. The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels. CNG channels are essential components of olfactory and visual transduction. In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP. In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP. CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel. CNG channels have been implicated in other areas. CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions. CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland. CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone.


Catalog Number: (89130-390)
Supplier: Ceodeux Inc.
Description: Used as a point of use for laboratory applications


Supplier: Kemtech America
Description: Manifolds are equipped with 4 mm double oblique, high vacuum solid glass stopcocks which are precision ground with corresponding numbers on barrel and plug.

Small Business Enterprise Minority or Woman-Owned Business Enterprise

Supplier: AmTab Manufacturing Corporation
Description: Whiteboard tables are used every day throughout the world in multi-purpose environments. High-quality state-of-the-art tables are safe, durable, easy to operate, and a great long-term value. Tables are perfect for heavy-use and heavy-turn settings providing years of trusted service.

Environmentally Preferable

Catalog Number: (76028-682)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series System for Cold Beverage Applications, Model BEV195 provides consistent quality water by reducing particulate* and chlorine taste and odor. The Sanitary Quick Change (SQC) encapsulated cartridge design allows for fast and easy cartridge change-outs without the need for a filter wrench. Designed for use in carbonator and cold beverage dispenser applications.


Catalog Number: (10303-574)
Supplier: Bioss
Description: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport, and maintain cellular volume. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter’s syndrome which is characterized by renal salt-wasting and low blood pressure.


Catalog Number: (10454-868)
Supplier: Bioss
Description: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.


Catalog Number: (10454-864)
Supplier: Bioss
Description: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.


Catalog Number: (76030-316)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge Kit, Model CARTPAK DP390 provides consistent high quality water by reducing particulate*, chlorine taste and odor, scale*, cyst**, and bacteria. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs. Includes three (3) HF90 cartridges and one (1) HF8–S cartridge.


Catalog Number: (89141-448)
Supplier: Enzo Life Sciences
Description: Ghrelin is a multifunctional peptide hormone secreted from the anterior pituitary known to affect many physiological processes including the release of growth hormone, appetite regulation, gastric acid secretion, gastrointestinal motility, and blood pressure regulation. The 28 amino acid ghrelin peptide is modified at Ser3 by addition of a fatty acid group (i.e., n-octanoyl) that is essential for its biological activity. The ghrelin receptor (GHS-R) is a seven transmembrane (7-TM) GPCR that is expressed in the hippocampus, pituitary, and hypothalamus, as well as in peripheral tissues including the heart, lung, liver, kidney, pancreas, intestines, and immune cells. Ghrelin signals are primarily relayed via coupling of the GHS-R to Gq/11 alpha subunits, promoting stimulation of phospholipase C, and an increase in intracellular calcium. Stimulation of adenylyl cyclases and increased cAMP are also induced by GHS-R activation. In humans and swine, two splice variants of the ghrelin receptor are expressed from the same gene. The GHS-R 1(a) receptor is the 366 amino acid, 7-TM form, while GHS-R 1(b) is a 289 amino acid, 5-TM form that is truncated at the C-terminus and is pharmacologically inactive. The epitope recognized by this antibody is unaffected by alternative splicing.


Catalog Number: (76028-664)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ high flow series replacement cartridge kit, model CARTPAK DP190 provides consistent high–quality water by reducing particulate, chlorine taste and odor, scale*, cyst**, and bacteria1. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs. Includes one (1) HF90 cartridge and one (1) HF8–S cartridge.


Catalog Number: (76031-628)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Aqua–Pure™ Whole House Large Diameter Stainless Steel Water Filter Housing SS8 EPE–316 L together with water filter cartridge filters all incoming water throughout an entire home or light commercial application. The housing design allows for use on both chlorinated (municipal) and non–chlorinated (well water) systems.


Supplier: Thermo Scientific
Description: This wireless monitoring solution for laboratory equipment safeguards the integrity of precious samples by continuously monitoring critical parameters and securely logging data to provide unprecedented peace-of-mind. Featuring audit trail traceability, this solution assists with conformance to 21 CFR Part 11, and other strenuous regulatory requirements for labs operating in regulated industries. System features software, modules, repeaters, receivers, and a 915 Mhz frequency (North America).

UL Listed cUL Listed CSA Certified

Catalog Number: (76028-692)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Aqua–Pure™ Whole House Sanitary Quick–Change Replacement Water Filter Cartridge AP917HD for the AP903 system as an activated carbon filter with a nominal heavy duty particulate reduction rating of 5 µm and a 100000 gallon capacity. This cartridge design is suitable for use on both chlorinated (municipal) and non–chlorinated (well water) systems.


Supplier: MP Biomedicals
Description: Storage: Room Temperature
2-Mercaptoethanol is a hybrid of ethylene glycol and 1,2-ethanedithiol. It is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals. It is widely used because the hydroxyl group confers solubility in water and lowers the volatility. Due to its diminished vapor pressure, its odour, while unpleasant, is less objectionable than related thiols.
2-Mercaptoethanol is used to reduce disulfide linkages in solubilizing proteins for gel electrophoresis (typically used in SDS-PAGE sample buffer at 5% concentration). Also it reduces excess oxidative polymerization of catalysts. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure. In solution, 2-mercaptoethanol is readily oxidized in air to a disulfide, especially at alkaline pH. Because of this property, it is widely used to protect proteins, enzymes in particular, from becoming inactive. An excess of 2-mercaptoethanol (generally used at 0.01 M) will maintain the protein thiol groups in their reduced state.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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