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Catalog Number: (10303-570)
Supplier: Bioss
Description: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport, and maintain cellular volume. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter’s syndrome which is characterized by renal salt-wasting and low blood pressure.


Catalog Number: (10300-516)
Supplier: Bioss
Description: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport, and maintain cellular volume. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter’s syndrome which is characterized by renal salt-wasting and low blood pressure.


Catalog Number: (10454-866)
Supplier: Bioss
Description: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.


Supplier: Restek
Description: Designed and intended specifically for use on LC-MS/MS systems, the Raptor™ ARC-18 column offers a well-balanced retention profile without the drawbacks of using an ordinary C18 in the harsh, acidic mobile phases needed for mass spectrometry (MS).

Catalog Number: (76028-658)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge, Model HF95–S provides consistent quality water by reducing particulate*, chlorine taste and odor, and scale*. Our Sanitary Quick Change (SQC) encapsulated design allows for easy cartridge change–outs without the need for a filter wrench.


Supplier: AmTab Manufacturing Corporation
Description: All-welded utility tables are used every day throughout the world in multi-purpose environments including schools, offices, and retail stores, high-quality state-of-the-art tables are safe, durable, easy to operate and perfect for heavy-use and heavy-turn settings providing years of trusted service.

Environmentally Preferable

Catalog Number: (76028-672)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge Kit, Model CARTPAK DP260 provides consistent high quality water by reducing particulate*, chlorine taste and odor, scale*, cyst**, and bacteria1. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs. Package includes two (2) HF60 cartridges and one (1) HF8–S cartridge.


Supplier: Corning
Description: Corning 50 ml centrifuge tubes made of PP or PET.
Supplier: AmTab Manufacturing Corporation
Description: All-welded computer tables are used every day throughout the world in multi-purpose media and tech environments. High-quality state-of-the-art tables are safe, durable, easy to operate, and a great long-term value. Tables are perfect for heavy-use and heavy-turn settings providing years of trusted service.

Environmentally Preferable

Catalog Number: (76030-698)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Under Sink Reverse Osmosis Water Filter System 3MRO501 is a multi-stage reverse osmosis water filter system that is NSF listed to reduce particulate, chlorine taste and odor, arsenic, barium, cadmium, chromium (both Hexavalent and Trivalent), copper, parasitic protozoan cysts, fluoride, lead, radium, selenium, p-Dichlorobenzene and toxaphene (both VOCs), TDS, turbidity and nitrate/nitrite.


Supplier: Thermo Scientific
Description: Thermo Scientific Hypersil GOLD™ aQ Polar endcapped C18 preparative columns are perfect for challenging reversed phase separations using highly aqueous mobile phases. The columns come in a wide range of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.

Catalog Number: (76028-666)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge Kit, Model CARTPAK DP290 provides consistent high quality water by reducing particulate*, chlorine taste and odor, scale*, cyst**, and bacteria1. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs. Includes two (2) HF90 cartridges and one (1) HF8–S cartridge.


Catalog Number: (76030-684)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Under Sink Reverse Osmosis Water Filter System 3MRO301 is a multi-stage reverse osmosis water filter system that is NSF certified to reduce particulate, chlorine taste and odor, arsenic, barium, cadmium, chromium (both Hexavalent and Trivalent), copper, parasitic protozoan cysts, fluoride, lead, radium, selenium, TDS and turbidity.


Supplier: WaterSaver Faucet
Description: Panel mounted valve and outlet fitting for installation on angle face of hood.

Catalog Number: (76028-694)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Aqua–Pure™ Whole House Sanitary Quick–Change Replacement Water Filter Cartridge AP917HD–S is suitable for the AP904 system as an activated carbon filter with a nominal particulate reduction rating of 5 microns. This cartridge design is suitable for use on both chlorinated (municipal) and non–chlorinated (well water) system.


Supplier: Brandtech
Description: These pipettors are the solution for many liquids that cannot be pipetted accurately with an air displacement pipet, such as viscous, volatile, or foaming liquids.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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