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Catalog Number: (10663-776)
Supplier: Bioss
Description: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.


Supplier: Restek
Description: These guard columns and transfer lines are designed to prevent water vapor from reaching the surface, preventing aggressive hydrolysis.

Catalog Number: (10002-056)
Supplier: Ansell Healthcare
Description: Excellent flexibility with optimal cut protection, the HyFlex® 11-724 glove features a 13G lightweight, medium-duty liner with INTERCEPT TECHNOLOGY® yarns that provide EN Cut Level 3 (ANSI Level 2) protection.


Supplier: HexArmor
Description: Innovative VS300S series protective eyewear is equipped with proprietary anti-fog coatings. These premium safety glasses, meant for a narrower face, feature seven side arm inclinations levels, allowing for a comfortable fit no matter the head shape.

Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ Water Filtration Products Reverse Osmosis Water Filtration System helps produce consistent Recipe Quality Water™ for hot beverages and steamers while maintaining efficient equipment operations in water conditions with high total dissolved solids (TDS) and/or hardness.

Supplier: Thermo Fisher Scientific
Description: Now silent and effortless, Thermo Scientific™ F1-ClipTip™ Variable Volume Pipettes feature newly enhanced volume adjustment, and the added confidence of ClipTip technology that locks tips firmly to the pipette with a complete seal.

Catalog Number: (10258-864)
Supplier: Bioss
Description: QRFP is a 136 amino acid secreted protein that is widely expressed in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis and thyroid, QRFP is a member of the RFamide neuropeptide family. QRFP may be involved in aldosterone secretion by the adrenal gland and is also implicated in stimulating metabolic rate, locomotor activity and increasing blood pressure. Considered a ligand for the G-protein coupled receptor GPR103, QRFP may have orexigenic activity, thereby acting as an appetite stimulant. The gene encoding QFRP is located on human chromosome 9, which consists of about 145 million bases, comprises roughly 4% of the human genome and encodes nearly 900 genes.


Catalog Number: (10258-866)
Supplier: Bioss
Description: QRFP is a 136 amino acid secreted protein that is widely expressed in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis and thyroid, QRFP is a member of the RFamide neuropeptide family. QRFP may be involved in aldosterone secretion by the adrenal gland and is also implicated in stimulating metabolic rate, locomotor activity and increasing blood pressure. Considered a ligand for the G-protein coupled receptor GPR103, QRFP may have orexigenic activity, thereby acting as an appetite stimulant. The gene encoding QFRP is located on human chromosome 9, which consists of about 145 million bases, comprises roughly 4% of the human genome and encodes nearly 900 genes.


Supplier: Restek
Description: Intermediate-polarity deactivated MXT® guard/retention gap columns are useful for a wide range of applications and are proven to be compatible with most common solvents.

Supplier: Kemtech America
Description: Manifolds feature a 14/20 outer joint at the center designed to fit a rubber septum

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Catalog Number: (10242-220)
Supplier: Bioss
Description: Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.


Catalog Number: (10242-216)
Supplier: Bioss
Description: Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.


Catalog Number: (76028-654)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge, Model HF90–S provides consistent high quality water by reducing particulate*, scale*, chlorine taste and odor, cyst**, and bacteria1. The Sanitary Quick Change (SQC) design allows for fast and easy cartridge change–outs without the need for a filter wrench.


Catalog Number: (76028-676)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series System for Cold Beverage Applications, Model BEV160 provides consistent high quality water by reducing particulate*, chlorine taste and odor, cyst**, and bacteria. The Sanitary Quick Change (SQC) design allows for easy cartridge change-outs. For use in cold beverage applications.


Catalog Number: (10390-816)
Supplier: Bioss
Description: PKA (or cAPK) is a cyclic AMP dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, plus gene transcription. PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunit (RI and RII) and three C subunit isoforms (C alpha, C beta, and C gamma) have been identified each possessing distinct cAMP binding properties and resulting in different phosphorylation states. C subunit is activated through autophosphorylation and direct phosphorylation at Thr197 by PDK-1. Tissue specific expression of C gamma, indicates pressure on C gamma during evolution, acting to modulate it in a functionally specific way. Certain amino acid substitutions make C gamma a distinct member of the cAMP dependent subfamily of protein kinases, and suggest that C gamma may be distinct in its protein substrate specificity or its interaction with the different regulatory subunits.


Catalog Number: (10091-594)
Supplier: Proteintech
Description: OPTN, also named as FIP2, GLC1E, HIP7, HYPL and NRP, plays a neuroprotective role in the eye and optic nerve. It is probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. OPTN may act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD). OPTN may constitute a cellular target for adenovirus E3 14.7, an inhibitor of TNF-alpha functions, thereby affecting cell death. Defects in OPTN are the cause of primary open angle glaucoma type 1E (GLC1E). Defects in OPTN are a cause of susceptibility to normal pressure glaucoma (NPG). OPTN mutated in adult-onset primary open angle glaucoma. It supports the protective role of OPTN in the trabecular meshwork.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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