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Catalog Number: (89142-052)
Supplier: Enzo Life Sciences
Description: Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson's disease.


Catalog Number: (10274-936)
Supplier: Bioss
Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].


Catalog Number: (10750-648)
Supplier: Prosci
Description: AGTR1 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.


Catalog Number: (10663-772)
Supplier: Bioss
Description: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.


Supplier: Welch Vacuum
Description: Complete oil-free vacuum system for rotary evaporators, concentrators, and other laboratory vacuum applications generating harsh chemical fumes

CSA Certified Product available on GSA Advantage®

Catalog Number: (76031-664)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ High Flow Series Replacement Cartridge, Model HF60–S provides consistent high quality water by reducing particulate*, chlorine taste and odor, scale*, cyst**, and bacteria1.


Catalog Number: (76031-696)
Supplier: SOLVENTUM PURIFICATION INC
Description: 3M™ CARTPAK for TFS450, Incl. Pre and Post Filter provides consistent quality water by reducing particulate and chlorine taste and odor. The Sanitary Quick Change (SQC) design allows for easy cartridge change–outs.


Catalog Number: (76116-782)
Supplier: Bioss
Description: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.


Supplier: PIP
Description: Lightweight, rimless design provides all day user comfort.

Catalog Number: (10799-600)
Supplier: Rockland Immunochemical
Description: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.


Catalog Number: (10315-598)
Supplier: Bioss
Description: G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.


Supplier: Bachem Americas
Description: The sequences given for angiotensin I (H-1680) and II (H-1705) correspond to the sequences of human, horse, sheep, pig, mouse, and rat angiotensins I and II.

Catalog Number: (14209-410)
Supplier: Wilmad-LabGlass
Description: Choose from 47mm or 90mm microfiltration FILTERWARE™ all-borosilicate glass filter apparatus consisting of a graduated funnel, a Standard Taper 40/35 glass joint connecting the coarse fritted filter support base to the filter flask, and an aluminum clamp (BP-1753).


Catalog Number: (BJBC075-200)
Supplier: Honeywell Research Chemicals
Description: BioSyn« products are ideal for DNA, RNA and oligonucleotide synthesis. All solvents and regents are filtered (0.2-micron) and tested for oxidation reage.

Supplier: Labconco
Description: Laboratory hoods feature sashes on two sides that, when mounted in an island or peninsular configuration, provide unobstructed viewing from either side during chemistry demonstrations or observing students using the hood

UL Listed Environmentally Preferable CSA Certified Product available on GSA Advantage®

Supplier: Thermo Scientific
Description: Maximize retention and loading using Thermo Scientific™ Hypersil™ PREP HS Si preparative HPLC columns.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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