You Searched For: pressure+hose

Supplier: Bel-Art Products

Description: With a removable, leak-proof plug made of chemical-resistant, non-stick Teflon® PTFE, these 2- and 3-way polypropylene plastic stopcocks have barbed tubulations that accep 6.4 to 9.5 mm (¼ to ⅜”") I.D.tubing.

Supplier: AVIDITY SCIENCE

Description: Reverse Osmosis (RO) Water in three convenient production rates: 20, 40, or 80 liters per hour.

Supplier: Chemglass

Description: Adapters are designed for use with vacuum manifolds and permit the manifold to be utilized with a multitude of standard glassware or tubing products.

Supplier: Argos Technologies

Description: Ergonomically designed endpieces provide simple and quick height adjustment.

Catalog Number: (76116-784)

Supplier: Bioss

Description: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.

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Catalog Number: (10349-066)

Supplier: Bioss

Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catalog Number: (10349-074)

Supplier: Bioss

Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catalog Number: (10274-930)

Supplier: Bioss

Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Supplier: GE Healthcare - Whatman

Description: The disposable Minimate™ TFF capsules, with Omega™ membrane, can perform concentration processes desalting or buffer exchange on the same system with minimal user intervention, and achieves high concentration factors in a single step due to the low hold-up volume of the devices.

Catalog Number: (10860-096)

Supplier: New Pig

Description: Material wraps completely around pipe to capture and contain sprays, drips and accumulated condensation.

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Catalog Number: (10315-602)

Supplier: Bioss

Description: G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.

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Catalog Number: (10802-112)

Supplier: Rockland Immunochemical

Description: The endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1), a member of the peptidase M1 family, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). It is also designated as adipocyte-derived leucine aminopeptidase (A-LAP), puromycin-insensitive leucine-specific aminopeptidase (PILS-AP) and aminopeptidase regulator of TNFR1 shedding (ARTS-1) (3). ERAP1 is localized to the lumen of the ER and induced by interferon. It may be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (3,4).

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Supplier: Saint Gobain Performance Plastics

Description: Pure-Fit® TC tube clamps are ideal for use in the pharmaceutical industry. They feature an outer body with no sharp edges, eliminating the potential for snags, scratches or punctures; a press-down locking system that is fully encapsulated to guard against untimely or unwanted release; and a side release mechanism that facilitates secure, single-handed installation and operation.

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Catalog Number: (76049-442)

Supplier: YSI

Description: This titrator is an appropriate motor-driven burette for manual titration and and precise dosing instrument for dispensable liquids, solvents and titrating agents. This is not only a stand-alone device, but also shows its strengths in the computer controlled 'Daisy Chain' network.

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Catalog Number: (102552-904)

Supplier: BioVendor

Description: Nesfatin-1 was first described in 2006 as a neurohormone derived from the protein NEFA/nucleobindin2 (NUCB2). It is a polypeptide consisting of 82 amino acids, with high level of homology in human, mouse and rat. Nesfatin-1 has been localized in the brain, particulary in the nuclei of the hypothalamus, in the adipose tissue and the gastrointestinal tract, but also in serum and cerebrospinal fluid. Nesfatin-1 was identified as a satiety molecule affecting fat metabolism. Intracerebroventricular administration of nesfatin-1 induces decreases in food intake and body weight and increases in sympathetic nerve activity and mean arterial pressure. Effect of Nesfatin-1 is leptin – independent, it is probably mediated by melanocortin system. Several studies are currently focused on the possibility of using Nesfatin-1 in the treatment of obesity, even in individuals with leptin resistence. Due to the presence in serum Nesfatin-1 could also serve as a clinical marker in the diagnosis of many diseases.

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Catalog Number: (103010-484)

Supplier: Anaspec Inc

Description: Renin, a highly specific aspartyl protease, cleaves angiotensinogen, produced in the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE (Angiotensin Converting Enzyme). Angiotensin II constricts blood vessels, leading to increased blood pressure. It also increases the secretion of ADH and aldosterone, and stimulates the hypothalamus to activate the thirst reflex. Since an overactive renin-angiotensin system leads to hypertension, renin is proposed as a therapeutic target for this disease.

Recombinant rat pro-renin was expressed in HEK cells. Purified enzyme was converted to the active renin by tryptic activation followed by removal of trypsin. The molecular mass of active rat renin is approximately 40 kDa. The activity of enzyme can be measured in FRET-based assays

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