You Searched For: oral+medication

Catalog Number: (76100-834)

Supplier: Bioss

Description: Human Papilloma virus (HPV) is responsible for the development of type and tissue specific papilloma in the oral cavity and in the larynx. In the skin papilloma virus can cause different types of warts and in the ano-genital region it is associated with condyloma or carcinoma. HPV types 16 and 18 seem to be responsible for the development of some carcinoma like cervical carcinoma.

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Supplier: Adipogen

Description: Masitinib is a potent, orally available protein tyrosine kinase inhibitor targeting c-Kit, PDGFR and FGFR3. It demonstrates activity for Kit and PDGFRalpha/beta with IC(50) values of 200nM, 540nM and 800nM respectively. It shows weak inhibition of ABL and c-Fms.

Catalog Number: (10749-928)

Supplier: Prosci

Description: SLPI Antibody: Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-kappa B activation by inhibiting Ikappa B degradation in the cytoplasm and competing for NF-kappa B binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.

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Supplier: Spectrum Chemicals

Description: Corn Oil, NF its uses include as a solvent vehicle for topical preparations and as a glidant excipient for oral dosage tablets and capsules. Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities

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Supplier: Adipogen

Description: PI3Kgamma is required for for T-cell and B-cell as well as mast cell migration and degranulation. As such, these kinases are attractive targets for potential anti-infmamatory drugs. TASP0415914 has shown excellent results in cell based assays. It is orally available and has performed will in murine in vivo models. PI3Kgamma IC(50) 29nM, AKT IC(50) 294nM.

Catalog Number: (470007-790)

Supplier: Kemtec

Description: You don’t have to take a field trip to the dentist to teach your students about tooth decay and preventive oral hygiene. With this kit, students will gain firsthand knowledge as they culture bacteria taken from their own teeth both before and after brushing. <BR><BR>Includes materials for 24 students<BR><BR>sterile petri dishes <BR>swabs<BR>agar<BR>mouthwash<BR>complete instructions.

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Catalog Number: (89416-300)

Supplier: Prosci

Description: SLPI Antibody: Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-kappa B activation by inhibiting I kappa B degradation in the cytoplasm and competing for NF-kappa B binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.

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Supplier: Adipogen

Description: NVP-BKM120 is a potent, selective, orally bioavailable Class I PI3Kalpha Inhibitor with IC(50) of 20nM, currently in Phase II clinical trials for the treatment of cancer. It exhibits lower potency against class III and class IV PI3Ks.

Catalog Number: (89150-540)

Supplier: Enzo Life Sciences

Description: More orally active than rutin. Vaso- and cardioprotective agent used clinically to treat venous disorders. Inhibits platelet aggregation. Protects biomembranes and DNA against the deleterious effects of γ-radiation. Free radical scavenger. Antioxidant.

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Catalog Number: (10425-704)

Supplier: Bioss

Description: May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili.

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Supplier: Selleck Chemicals

Description: MLN9708 gets hydrolyzed to its biologically active form MLN2238, on exposure to aqueous solutions or plasma

Supplier: Adipogen

Description: JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with an IC(50) of 40nM. It also inhibits closely related tyrosine kinases such as Ret (IC(50) of 180nM) and Kit (C50 of 500nM). It has no significant activity (<gt/>1µM) against VEGFR-1 and VEGFR-3.

Supplier: Adipogen

Description: Potent and highly selective Bruton's tyrosine kinase (BTK) inhibitor. Orally bioavailable and irreversible inhibitor of BTK (IC50 = 0.5 nM) with antineoplastic activity. Binds to and irreversibly inhibits BTK activity, preventing B cell activation and B cell-mediated signaling. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. Shown to inhibit autophosphorylation of BTK (IC50 = 11nM), phosphorylation of PLCgamma (IC50 = 29nM), a substrate of BTK and phosphorylation of ERK (IC50 = 13nM).

Supplier: Bachem Americas

Description: These dipeptides may potentially serve as drug carriers to facilitate diffusion across the blood-brain barrier. Both peptides well permeate through gastro-intestinal lipid membranes, the acidic molecule permeating slower than the ester derivative. As their peptide bonds are stable, both dipeptides are suitable for oral administration.

Catalog Number: (10083-430)

Supplier: Proteintech

Description: Zinc-alpha-2-glycoprotein (AZGP1) is a soluble protein normally found in body fluids, functions as a lipid mobilizing factor . It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens . AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors .

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Catalog Number: (75789-454)

Supplier: Prosci

Description: Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen beta -chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.

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