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Image Unavailable-10666-932

Anti-HNRNPA2B1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10666-932)
Supplier: Bioss
Description: Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleous.
Product Image-10107-364

Anti-USP39 Rabbit Polyclonal Antibody

Catalog Number: (10107-364)
Supplier: Prosci
Description: USP39 may play a role in mRNA splicing. It is unsure if the protein really exhibits hydrolase activity. It could be a competitor of ubiquitin C-terminal hydrolases
Image Unavailable-10666-934

Anti-HNRNPA2B1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10666-934)
Supplier: Bioss
Description: Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleous.
Image Unavailable-10491-936

Anti-RBM20 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10491-936)
Supplier: Bioss
Description: RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin).
Image Unavailable-10491-942

Anti-RBM20 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10491-942)
Supplier: Bioss
Description: RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin).
Image Unavailable-10491-932

Anti-RBM20 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10491-932)
Supplier: Bioss
Description: RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin).
Product Image-10102-322

Anti-GEMIN2 Rabbit Polyclonal Antibody

Catalog Number: (10102-322)
Supplier: Prosci
Description: Part of the core SMN complex which plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
Image Unavailable-76110-872

Anti-RBM20 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76110-872)
Supplier: Bioss
Description: RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin).
Image Unavailable-10373-392

Anti-YB1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10373-392)
Supplier: Bioss
Description: Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
Image Unavailable-10086-714

Anti-EXOSC2 Mouse Monoclonal Antibody [clone: 1G8B1]

Catalog Number: (10086-714)
Supplier: Proteintech
Description: In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs . EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events .
Product Image-10373-374

Anti-YB1 Rabbit Polyclonal Antibody

Catalog Number: (10373-374)
Supplier: Bioss
Description: Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
Image Unavailable-10373-396

Anti-YB1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10373-396)
Supplier: Bioss
Description: Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
Image Unavailable-75931-052

Anti-PLAC4 Rabbit Polyclonal Antibody

Catalog Number: (75931-052)
Supplier: Rockland Immunochemical
Description: PLAC4 (placenta-specific protein 4), was initially discovered as a gene whose mRNA was expressed in placental syncytiotrophoblast and choriocarcinoma cells. While the function of PLAC4 is currently unclear, its gene is known to be located on chromosome 21q22.3. Due to the PLAC4 gene location on chromosome 21 and the release of its mRNA transcripts into maternal bloodstream from the placenta, it has been proposed to be a useful marker noninvasive prenatal chromosome 21 aneuploidy detection, although other reports suggests that PLAC4 mRNA levels are not altered in the maternal circulation of pregnancies with trisomy 21.
Image Unavailable-10459-390

Anti-SAP62 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10459-390)
Supplier: Bioss
Description: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Image Unavailable-10459-386

Anti-SAP62 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10459-386)
Supplier: Bioss
Description: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Image Unavailable-75788-662

Human Recombinant Partner of Y14 and Mago (from E. coli)

Catalog Number: (75788-662)
Supplier: Prosci
Description: Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for the intron exon structure of genes, and directs post-transcriptional processes in the cytoplasm, for instance mRNA export, nonsense-mediated mRNA decay or translation. WIBG is a cytoplasmic RNA-binding protein, it can be excluded from nucleus by Crm1. WIBG as a cooperateing partner of Mago-14, relates with Mago-14 by its N-terminal domain.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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