You Searched For: mRNA

Catalog Number: (102902-442)

Supplier: New England Biolabs (NEB)

Description: Most eukaryotic mRNAs require a 7-methyl guanosine (m7G) cap structure at the 5´ end and a Poly(A) tail at the 3´ end to be efficiently translated.

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Catalog Number: (102902-440)

Supplier: New England Biolabs (NEB)

Description: Most eukaryotic mRNAs require a 7-methyl guanosine (m7G) cap structure at the 5´ end and a poly(A) tail at the 3´ end to be efficiently translated.

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Catalog Number: (97064-712)

Supplier: VWR

Description: Phenol / Chloroform #2- A 25:24:1 mixture of phenol, chloroform, and isoamyl alcohol useful for preparing RNA with maximal recovery of poly (A+) RNA for subsequent mRNA purification and generation of cDNA.

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Supplier: New England Biolabs (NEB)

Description: mRNA Cap 2´-O-Methyltransferase adds a methyl group at the 2´-O position of the first nucleotide adjacent to the cap structure at the 5´ end of the RNA

Catalog Number: (103268-090)

Supplier: Novus Biologicals

Description: The C4orf21 / prematurely terminated mRNA decay factor-like Antibody from Novus Biologicals is a rabbit polyclonal antibody to C4orf21 / prematurely terminated mRNA decay factor-like. This antibody reacts with human. The C4orf21 / prematurely terminated mRNA decay factor-like Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.

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Catalog Number: (75790-708)

Supplier: Prosci

Description: Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.

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Catalog Number: (76447-140)

Supplier: New England Biolabs (NEB)

Description: mRNA Decapping Enzyme decaps m7G-capped mRNA producing a 5′ monophosphate end.

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Supplier: SGI - DNA Synthetic Genomics

Description: The BioXp Select mRNA synthesis kit enables the synthesis of mRNA from an input DNA template.

Supplier: AAT BIOQUEST INC

Description: Transfectamine™ mRNA Transfection reagent is a powerful and versatile transfection reagent designed to introduce a higher amount of mRNA into eukaryotic cells, or more specifically, into animal cells.

Catalog Number: (102111-272)

Supplier: Novus Biologicals

Description: The pre-mRNA cleavage factor I (59 kDa subunit) Antibody from Novus Biologicals is a rabbit polyclonal antibody to pre-mRNA cleavage factor I (59 kDa subunit). This antibody reacts with human, mammal. The pre-mRNA cleavage factor I (59 kDa subunit) Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin.

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Supplier: Quantabio

Description: Ultra-sensitive mRNA library prep workflow with efficient poly(A) capture.

Supplier: Polyplus Transfection

Description: jetMESSENGER® is a mRNA transfection reagent that has been specifically designed to offer outstanding transfection efficiency in cells that are usually hard to transfect, allowing relevant gene expression experiments in all cell types.

Supplier: SGI - DNA Synthetic Genomics

Description: The BioXp Select mRNA synthesis kit enables the synthesis of mRNA from an input DNA template.

Supplier: GE Healthcare - Life Sciences

Description: Sera-Mag Oligo(dT)-Coated Magnetic Particles enable convenient mRNA isolation and extraction. Sera-Mag Oligo(dT) Magnetic Particles bind target mRNA through pairing of the polyadenylated RNA tail found on the 3’ end of mRNA to the covalently bound oligo(dT) groups on the surface of the particles. This binding is easily accomplished using standard hybridisation conditions. Versatile and efficient methods for mRNA purification are critical, given that eukaryotic mRNA makes up only 1 to 3% of total cellular RNA. Sera-Mag Oligo(dT) Magnetic Particles remove 90% or more of mRNA from total RNA with just one extraction.

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Catalog Number: (10101-714)

Supplier: Prosci

Description: LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.

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Catalog Number: (76100-646)

Supplier: Bioss

Description: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.

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