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Product Image-10099-930

Anti-DGCR2 Rabbit Polyclonal Antibody

Catalog Number: (10099-930)
Supplier: Prosci
Description: Deletions of the 22q11.2 have been associated with a wide range of developmental defects classified under the acronym CATCH 22. The DGCR2 is a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
Image Unavailable-10095-752

Anti-TCTN3 Rabbit Polyclonal Antibody

Catalog Number: (10095-752)
Supplier: Proteintech
Description: TCTN3 (tectonic-3 or TECT3) is a type I membrane protein that belongs to the tectonic family, which consists of TCTN1, TCTN2 and TCTN3. Studies in mice suggest that tectonic may be involved in Hedgehog (Hh) signaling, and essential for ciliogenesis. Tectonic is component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. TCTN3 is necessary for transduction of the sonic hedgehog (SHH) signaling pathway. Orofaciodigital syndromes (OFDSs) consist of a group of heterogeneous disorders characterized by abnormalities in the oral cavity, face, and digits and associated phenotypic abnormalities. Recently, TCTN3 mutations are found as the cause of an extreme form of OFD associated with bone dysplasia, tibial defect, cystic kidneys, and brain anomalies.
Image Unavailable-76324-156

FACE SHIELD F40 PROPIONATE 915-63 GREEN

Catalog Number: (76324-156)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD F40 PROPIONATE 915-63 GREEN
Image Unavailable-76324-164

FACE SHIELD F30 ACETATE 3440 BULK BX50

Catalog Number: (76324-164)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD F30 ACETATE 3440 BULK BX50
Image Unavailable-76558-900

BUMP CAP FACE SHIELD COMPAT WHITE CS12

Catalog Number: (76558-900)
Supplier: Sellstrom
Description: BUMP CAP FACE SHIELD COMPAT WHITE CS12
Image Unavailable-76324-174

FACE SHIELD ECONOMY F10 PETG 8X15 1/2IN

Catalog Number: (76324-174)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD ECONOMY F10 PETG 8X15 1/2IN
Image Unavailable-76324-160

FACE SHIELD F40 PROPIONATE 915-60 CS50

Catalog Number: (76324-160)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD F40 PROPIONATE 915-60 CS50
Image Unavailable-76324-152

FACE SHIELD F30 ACETATE CLR 15 1/2X9 IN

Catalog Number: (76324-152)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD F30 ACETATE CLR 15 1/2X9 IN
Image Unavailable-76558-982

FACE SHIELD ASSMBLY 301 CLEAR PCB WINDOW

Catalog Number: (76558-982)
Supplier: Sellstrom
Description: FACE SHIELD ASSMBLY 301 CLEAR PCB WINDOW
Image Unavailable-76558-596

FACE SHIELD WINDOW PETG 9X15.5X.04 CS50

Catalog Number: (76558-596)
Supplier: Sellstrom
Description: FACE SHIELD WINDOW PETG 9X15.5X.04 CS50
Image Unavailable-76558-826

FACE SHIELD WINDOW 390 CLEAR AF 8X12

Catalog Number: (76558-826)
Supplier: Sellstrom
Description: FACE SHIELD WINDOW 390 CLEAR AF 8X12
Image Unavailable-76558-662

FACE SHIELD WIND ACETATE 8X12X.04 CS24

Catalog Number: (76558-662)
Supplier: Sellstrom
Description: FACE SHIELD WIND ACETATE 8X12X.04 CS24
Image Unavailable-76558-780

FACE SHIELD WINDOW PETG 8X15.5X.035 CS96

Catalog Number: (76558-780)
Supplier: Sellstrom
Description: FACE SHIELD WINDOW PETG 8X15.5X.035 CS96
Product Image-10796-994

Human Recombinant Annexin A51 (from E. coli)

Catalog Number: (10796-994)
Supplier: Prosci
Description: Anexin A5 is a phospholipid binding protein, which binds with high affinity and selectivity to PS in the presence of calcium. PS is predominantly located in membrane leaflets, which face the cytosol. However, recent findings show that each cell type has the molecular machinery to expose PS at its cell surface. This machinery is activated during the execution of apoptosis. Once PS is exposed at the cell surface it exhibits procoagulant and proinflammatory activities. Anexin A5 will bind to the PS-exposing apoptotic cell and can inhibit the procoagulant and proinflammatory activities of the dying cell. Anexin A5 has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Anexin A5 is associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).
Product Image-10796-992

Human Recombinant Annexin A5 (from E. coli)

Catalog Number: (10796-992)
Supplier: Prosci
Description: Anexin A5 is a phospholipid binding protein, which binds with high affinity and selectivity to PS in the presence of calcium. PS is predominantly located in membrane leaflets, which face the cytosol. However, recent findings show that each cell type has the molecular machinery to expose PS at its cell surface. This machinery is activated during the execution of apoptosis. Once PS is exposed at the cell surface it exhibits procoagulant and proinflammatory activities. Anexin A5 will bind to the PS-exposing apoptotic cell and can inhibit the procoagulant and proinflammatory activities of the dying cell. Anexin A5 has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Anexin A5 is associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).
Product Image-10070-660

Anti-RAB25 Mouse Monoclonal Antibody [clone: 3F12F3]

Catalog Number: (10070-660)
Supplier: Prosci
Description: Members of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Rab25 was cloned from a gastric parietal cell cDNA library and is expressed in epithelial tissues such as the gastrointestinal mucosae, kidney, and lung, which encoded a protein of 28 kDa.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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