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Catalog Number: (75932-158)
Supplier: Rockland Immunochemical
Description: Serine palmitoyltransferase (SPT), which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPT2 is the long chain base subunit 2 of mammalian serine palmitoyltransferase. SPT2 is catalytically active but needs its related protein SPT1 for its stabilization and anchoring the holoenzyme to the cytosolic face of the endoplasmic reticulum. As in the case with SPT1, mutations in the SPT2 gene can cause hereditary sensory and autonomic neuropathy type I (HSAN-I), resulting from a loss of SPT activity as well as the accumulation of the atypical and neurotoxic sphingoid metabolite 1-deoxy-sphinganine.


Supplier: Promocell, Inc.
Description: Primary Normal Human Epidermal Keratinocytes (NHEK) are isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs. They are the major cell type in the epidermis, making up about 90% of the cells. Epidermal keratinocytes originate in the stratum basale and move up through the layers of the epidermis. During this movement, they undergo gradual differentiation and morphology changes until they reach the stratum corneum, where they form a layer of nucleus-free, flat, and highly keratinized squamous cells. This layer forms an effective barrier to the entry of infectious agents into the body and minimizes moisture loss.

Catalog Number: (10751-318)
Supplier: Prosci
Description: SPT2 Antibody: Serine palmitoyltransferase (SPT), which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPT2 is the long chain base subunit 2 of mammalian serine palmitoyltransferase. SPT2 is catalytically active but needs its related protein SPT1 for its stabilization and anchoring the holoenzyme to the cytosolic face of the endoplasmic reticulum. As in the case with SPT1, mutations in the SPT2 gene can cause hereditary sensory and autonomic neuropathy type I (HSAN-I), resulting from a loss of SPT activity as well as the accumulation of the atypical and neurotoxic sphingoid metabolite 1-deoxy-sphinganine.


Catalog Number: (MSPP-8ZEN3)
Supplier: Grainger
Description: SHIELD FACE RATCHET UNCOATED PC WHITE


Catalog Number: (76324-158)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD F20 PC CLEAR 8 INX15 1/2 IN


Catalog Number: (76558-554)
Supplier: Sellstrom
Description: FACE SHIELD ASSMBLY MAXVIEW CLEAR AF


Catalog Number: (76559-040)
Supplier: Sellstrom
Description: FACE SHIELD ASSMBLY 390 CLEAR 8X12


Catalog Number: (76559-034)
Supplier: Sellstrom
Description: FACE SHIELD ASSMBLY DP4 FOR HARD HAT


Catalog Number: (76559-038)
Supplier: Sellstrom
Description: FACE SHIELD ASSMBLY FOR HH QUAD500 AF


Catalog Number: (76324-670)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD F30 ACETATE SCHEDULE B VISOR


Catalog Number: (76324-154)
Supplier: Safety & Industrial Supplies
Description: FACE SHIELD F40 PROPIONATE 15 1/2X9 IN


Catalog Number: (76324-126)
Supplier: Safety & Industrial Supplies
Description: HEADGEAR FACE SHIELD MODEL K HDG10 CS60


Catalog Number: (76558-632)
Supplier: Sellstrom
Description: FACE SHIELD HEAD GEAR MODEL 301


Catalog Number: (76558-700)
Supplier: Sellstrom
Description: FACE SHIELD ASSMBLY MAXLIGHT AF FOR HH


Catalog Number: (77439-016)
Supplier: Bioss
Description: The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.


Catalog Number: (MSPP-S-23868)
Supplier: ULINE MS
Description: SHIELD FACE DISPOSABLE ECONOMY PP CS25


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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