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Catalog Number: (89358-776)
Supplier: Genetex
Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. [provided by RefSeq]


Catalog Number: (10452-560)
Supplier: Bioss
Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.


Catalog Number: (10452-558)
Supplier: Bioss
Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.


Catalog Number: (10452-550)
Supplier: Bioss
Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.


Catalog Number: (MSPP-MA485MI21)
Supplier: CLOUD-CLONE CORP MS
Description: Monoclonal Antibody to N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP), derived from KLH conjugated NT-ProBNP, is reactive with Human/Mouse/Rat/Pig.

New Product


Catalog Number: (76118-612)
Supplier: Bioss
Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.


Catalog Number: (10452-554)
Supplier: Bioss
Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.


Catalog Number: (10466-110)
Supplier: Bioss
Description: MFF belongs to the tango11 family and plays a role in mitochondrial and peroxisomal fission. It is highly expressed in heart, kidney, liver, brain, muscle and stomach. There are five named isoforms.


Catalog Number: (89417-656)
Supplier: Prosci
Description: APBA2 Antibody: APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.


Catalog Number: (IC10157825)
Supplier: MP Biomedicals
Description: L-3,4-Dihydroxyphenylalanine (L-DOPA), an anti-Parkinsonian agent, is the natural isomer of the immediate precursor to dopamine. L-DOPA is the product of the hydroxylation of L-tyrosine by tyrosine hydroxylase in brain and in adrenal medulla.

SDS


Catalog Number: (10069-072)
Supplier: Prosci
Description: Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.


Catalog Number: (10751-128)
Supplier: Prosci
Description: APBA2 Antibody: APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.


Catalog Number: (10456-080)
Supplier: Bioss
Description: Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.Tissue specificity: Widely expressed with highest levels in heart, brain and skeletal muscle.


Catalog Number: (MSPP-PAA11MI01)
Supplier: CLOUD-CLONE CORP MS
Description: Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF), derived from recombinant BDNF (Pro20~Arg252), is reactive with Human/Mouse/Rat/Rabbit/Pig/Goat/Horse.

New Product


Catalog Number: (100503-692)
Supplier: Electron Microscopy Sciences
Description: Can be used for staining synapses (Pfenninger, K., Sandri, C., Albert, K. and Eugster, C.H., 1969). Contribution of the problem of structural organization of the presynaptic area (Brain Res., 12:10).

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Catalog Number: (10452-552)
Supplier: Bioss
Description: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.


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