You Searched For: bra20

Catalog Number: (103287-818)

Supplier: Novus Biologicals

Description: The GPR148 Antibody from Novus Biologicals is a rabbit polyclonal antibody to GPR148. This antibody reacts with human. The GPR148 Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.

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Catalog Number: (103286-444)

Supplier: Novus Biologicals

Description: The Kv12.2 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Kv12.2. This antibody reacts with human. The Kv12.2 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.

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Catalog Number: (10264-266)

Supplier: Bioss

Description: Cortexin 1 and Cortexin 3 are single-pass membrane proteins. Cortexin 1 may be involved in mediating extracellular or intracellular signaling of cortical neurons during forebrain development. Cortexin 3 is specifically expressed in kidney and brain. Exsiting as two isoforms due alternative splicing, cortexin 3 may mediate extracellular or intracellular signaling in the kidney or brain.

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Supplier: Adipogen

Description: Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM1 is a major sialoglycolipid of neuronal membranes that modulates calcium homeostasis and which is important for neuronal plasticity and repair mechanisms. It binds to cholera toxin B subunit, resulting in stimulation of adenylyl cyclase in a wide variety of cell types. After cholera toxin binds to membrane associated Monosialoganglioside GM1, the A subunit of cholera toxin is translocated to the cell interior, where it catalyzes the ADP ribosylation of the membrane associated Gs subunit of adenylyl cyclase. In addition, binding of cholera toxin to monosialoganglioside GM1 causes translocation of NF-kappaB and activation of dendritic cells. E. coli heat-labile enterotoxin (LT) is structurally and functionally similar to cholera toxin and binds GM1 as well. GM1 has also been shown to improve Parkinson's disease symptoms and slow it's progression.

Catalog Number: (10269-926)

Supplier: Bioss

Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

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Catalog Number: (80057-868)

Supplier: MilliporeSigma

Description: Principal pigment of bile and one of the major end products of hemoglobin decomposition. Contains conjugated double bonds and reactive hydrogen atoms. Proposed to serve as a physiological antioxidant. Reported to pass through the blood-brain barrier and exert significant antioxidant effects in the brain. Extinction coefficient (454nm, trichloromethane): 59,100–62,300 M-1cm-1.

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Catalog Number: (103307-832)

Supplier: Novus Biologicals

Description: The POU6F1 Antibody (6F10) from Novus Biologicals is a mouse monoclonal antibody to POU6F1. This antibody reacts with human. The POU6F1 Antibody (6F10) has been validated for the following applications: Western Blot, ELISA.

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Catalog Number: (10667-022)

Supplier: Bioss

Description: The β-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer’s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.

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Catalog Number: (103293-848)

Supplier: Novus Biologicals

Description: The nNOS Antibody (60718) [DyLight 680] from Novus Biologicals is a mouse monoclonal antibody to nNOS. This antibody reacts with human, mouse, rat. The nNOS Antibody (60718) [DyLight 680] has been validated for the following applications: Western Blot.

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Catalog Number: (10269-940)

Supplier: Bioss

Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

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Catalog Number: (10269-938)

Supplier: Bioss

Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

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Catalog Number: (10032-366)

Supplier: OMNI INTERNATIONAL

Description: Bead beating is the most effective and verstile lysis method available.

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Catalog Number: (103309-832)

Supplier: Novus Biologicals

Description: The SCN3A Antibody (2F8) from Novus Biologicals is a mouse monoclonal antibody to SCN3A. This antibody reacts with human. The SCN3A Antibody (2F8) has been validated for the following applications: Western Blot, ELISA.

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Catalog Number: (10274-152)

Supplier: Bioss

Description: Acid sensing ion channel ASIC1 is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7- and 3.7-kb transcripts in brain and spinal cord tissues. ASIC3, also designated SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation. ASIC4, also designated ACCN4 and BNAC4, is abundant in pituitary gland and is also present in the inner ear.

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Catalog Number: (10274-184)

Supplier: Bioss

Description: Acid sensing ion channel ASIC1 is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7- and 3.7-kb transcripts in brain and spinal cord tissues. ASIC3, also designated SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation. ASIC4, also designated ACCN4 and BNAC4, is abundant in pituitary gland and is also present in the inner ear.

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Catalog Number: (10782-378)

Supplier: Biosensis

Description: FUNCTION: Associates specifically with huntingtin. This binding is enhanced by an expanded polyglutamine repeat. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: In the brain, especially in the olfactory bulb and in the brain stem. No detectable expression in peripheral tissues such as lung, testis, spleen, and small intestine. SIMILARITY: Contains 1 HAP1 N-terminal domain.

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