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Supplier: Biotium
Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF488A, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 100uL

Supplier: Biotium
Description: S100, Monoclonal antibody, Clone: 4C4.9, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF405S, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, IHC Western, Size: 500uL

Catalog Number: (89415-822)
Supplier: Prosci
Description: Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.


Supplier: Biotium
Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF405S, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 100uL

Catalog Number: (10251-146)
Supplier: Bioss
Description: Dbx1 homeodomain transcription factor is expressed in progenitors at the boundary between the dorsal and ventral plates of the caudal neural tube, from which postmitotic cells migrate tangentially to their final destination. Dbx1 is implicated in patterning the central nervous system during embryogenesis. Cell fate allocation and cell diversity are determined at very early stages in progenitor cells at precise coordinates along the dorsoventral and anteroposterior axis. In the spinal cord, the spatially restricted expression of Dbx1 in progenitors is critical in establishing interneuron cell fates and helps coordinate diverse phenotypic features. In the telencephalon, Dbx1 is expressed in restricted progenitor domains at the borders of the developing pallium.


Catalog Number: (10263-302)
Supplier: Bioss
Description: Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss. SCA is caused by the expansion of a translated CAG repeat, encoding a polyglutamine tract in SCA gene products, known as ataxins. The ataxin proteins are ubiquitously expressed in nervous tissue, but are primarily detected in cerebellum, brain stem and spinal cord in the central nervous system. Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins. A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons. Ataxin-10 interacts with p110, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain. Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures. SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene.


Catalog Number: (10253-580)
Supplier: Bioss
Description: Probable regulator of calmodulin signaling.


Catalog Number: (103521-250)
Supplier: IXCELLS BIOTECHNOLOGIES USA MS
Description: Rat Astrocytes (RA); Frozen


Catalog Number: (76009-500)
Supplier: Prosci
Description: PRSS3 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. PRSS3 is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.


Catalog Number: (10269-136)
Supplier: Bioss
Description: SRPX2 is a 465 amino acid secreted protein expressed in neurons of the brain, including the rolandic area. It has been suggested that SRPX2 enhances cell motility, migration and adhesion through FAK signaling in gastric and other cancer cells. Localized to the cytoplasm, SRPX2 is a ligand for uPAR (urokinase plasminogen activator), a receptor that is a crucial component of the extracellular plasminogen proteolysis system. SRPX2 may be responsible for rolandic seizures (RSs) associated with oral and speech dyspraxia and mental retardation (MR). The involvement of SRPX2 in these disorders suggests an important role for SRPX2 in the perisylvian region critical for language and cognitive development.


Supplier: Biotium
Description: S100, Monoclonal antibody, Clone: 4C4.9, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF640R, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, IHC Western, Size: 500uL

Supplier: Biotium
Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF647, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 500uL

Supplier: Biotium
Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF568, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 500uL

Supplier: Biotium
Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF594, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 100uL

Catalog Number: (10488-128)
Supplier: Bioss
Description: Glycolysis is an evolutionarily conserved series of ten chemical reactions that utilizes eleven enzymes to concomitantly generate pyruvate and ATP from glucose. fructose kinase-2/fructose 2,6-bisphosphatase (PFK-2) stimulates the synthesis and degradation of fructose 2,6-bisphosphate. Glycogen phosphorylase (also known as GP) is an allosteric enzyme important in carbohydrate metabolism. Its activity is regulated through either noncovalent binding of metabolites or by covalent modification. Glycogen phosphorylase catalyzes the phosphorylation of glycogen to Glc-1-P. There are three genes which encode the brain, liver and muscle forms of glycogen phosphorylase, PYGB, PYGL and PYGM. Because of its fundamental role in the metabolism of glycogen, glycogen phosphorylase has been a target for the design of inhibitory compounds, which could be valuable in the therapeutic treatment of type 2 diabetes mellitus.


Supplier: Biolegend
Description: Tau Phospho (Ser396) Monoclonal Antibody, host: Mouse, Clone: PHF-13, Reactivity: Human, Isotype: IgG2b, Conjugate: Alexa Fluor 647, immunogen: was raised using PHF-tau preparations from human brain, Application: IHC-P, Synonyms: Microtubule-associated protein tau, Size: 25 ug

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