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Catalog Number: (10458-572)
Supplier: Bioss
Description: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC12 (zinc finger, DHHC domain containing 12), also known as ZNF400, is a 267 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to a S-palmitoyl protein and free CoA. Three isoforms exist due to alternative splicing events. The gene encoding ZDHHC12 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Chromosome 9 is considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype.


Catalog Number: (89416-138)
Supplier: Prosci
Description: Slug Antibody: Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis. Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-. More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival. Furthermore, Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family. Slug antibody has no cross-reactivity to Snail protein.


Catalog Number: (75934-306)
Supplier: Rockland Immunochemical
Description: ZBTB1 is a zinc finger protein that also contains BTB (BR-C, ttk and bab) domain. While little is known about this protein or the related protein ZBTB2, its expression is known to be down-regulated in human bronchial epithelial cells in response to the presence of Vanadium. Recently, expression of variant ZBTB1 protein has been associated with increased age-related macular degeneration.


Supplier: Thermo Scientific
Description: Orion™ AQUAfast Tablet Reagents perform colorimetric measurements of common water parameters with convenient, rapidly dissolving tablets.

Catalog Number: (76011-536)
Supplier: Prosci
Description: ZNF593 negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins.


Supplier: Janitorial Supplies
Description: The Rubbermaid Commercial Products BRUTE Bucket allows you to easily transport liquids.

Catalog Number: (200062-466)
Supplier: Enzo Life Sciences
Description: SOD (Superoxide dismutase) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells, they are: EC SOD (extracellular SOD), Cu/Zn SOD (copper and zinc-containing SOD) and Mn SOD (manganese-containing SOD).


Catalog Number: (75933-686)
Supplier: Rockland Immunochemical
Description: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB40, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Single nucleotide polymorphisms near ZBTB40 have been linked to differences in bone mineral density of the hip and lumbar spine, and had a significant association with low-trauma fractures suggesting that ZBTB40 may be involved in bone development and formation.


Catalog Number: (10110-474)
Supplier: Prosci
Description: TOE1 belongs to the CAF1 family and 1 C3H1-type zinc finger. TOE1 inhibits cell growth rate and cell cycle. It induces CDKN1A expression as well as TGF-beta expression and mediates the inhibitory growth effect of EGR1.


Catalog Number: (76010-776)
Supplier: Prosci
Description: ZNF665 may be involved in transcriptional regulation.


Catalog Number: (10241-918)
Supplier: Bioss
Description: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-1, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.


Catalog Number: (10108-482)
Supplier: Prosci
Description: SF1 contains 1 KH domain and 1 CCHC-type zinc finger. It is necessary for the ATP-dependent first step of spliceosome assembly and binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. It may act as transcription repressor.


Catalog Number: (TCB0785-5G)
Supplier: TCI America
Description: [for Biochemical Research]
CAS Number: 55663-99-5
MDL Number: MFCD00074762
Molecular Formula: C15H14ClN3O3
Molecular Weight: 775.77
Purity/Analysis Method: >95.0% (T)
Form: Crystal

SDS


Catalog Number: (10433-108)
Supplier: Bioss
Description: The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified.


Catalog Number: (89329-186)
Supplier: Genetex
Description: Rabbit polyclonal antibody to ZNF536


Catalog Number: (89322-686)
Supplier: Genetex
Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: IHC-P, WB Pkg Size: 100 ul


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