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Catalog Number: (10668-490)
Supplier: Bioss
Description: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF10 (ring finger protein 10), also known as RIE2, is an 811 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Existing as multiple alternatively spliced isoforms, RNF10 interacts with MOX-2 and is thought to regulate its transcription in schwann cells, possibly playing a role in myelin formation. The gene encoding RNF10 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.


Catalog Number: (10668-384)
Supplier: Bioss
Description: Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.


Catalog Number: (76119-242)
Supplier: Bioss
Description: ZNF420 contains 19 C2H2-type zinc fingers and 1 KRAB domain. It may be involved in transcriptional regulation. It is a negative regulator of p53-mediated apoptosis.


Catalog Number: (103259-570)
Supplier: Novus Biologicals
Description: The SALL4 Antibody from Novus Biologicals is a rabbit polyclonal antibody to SALL4. This antibody reacts with human. The SALL4 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (10082-562)
Supplier: Proteintech
Description: AEBP2 belongs to the AEBP2/jing C2H2-type zinc-finger family. It is a DNA-binding transcriptional repressor. AEBP2 is a zinc finger protein that has been shown to interact with the mammalian Polycomb Repression Complex 2 (PRC2). It may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. AEBP2 is an evolutionarily well-conserved gene that is found in the animals ranging from flying insects to mammals. The antibody is special to AEBP2.


Catalog Number: (10259-262)
Supplier: Bioss
Description: Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.


Catalog Number: (103269-228)
Supplier: Novus Biologicals
Description: The ZNF184 Antibody from Novus Biologicals is a rabbit polyclonal antibody to ZNF184. This antibody reacts with human. The ZNF184 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Supplier: VWR International
Description: No need to buy two fitting halves.

Catalog Number: (75790-636)
Supplier: Prosci
Description: Zinc Finger BED Domain-Containing Protein 1 (ZBED1) contains one BED-type zinc finger and is found in the cell nucleus. ZBED1 is widely expressed, highly in heart, skeletal muscle, spleen and placenta. The expression of ZBED1 is usually linked to the cell cycle. During the G1/S phase, the expression is increasing. During the S/G2 phage, the expression reaches to the highest, and then decreasing. ZBED1 exists in homodimer forms, which can bind to 5’-TGTCCG[CT]GA[CT]A-3’ DNA elements, that can be found in the promoter regions of a number of gene related to cell proliferation.


Supplier: VWR International
Description: No need to buy two fitting halves.

Catalog Number: (103285-848)
Supplier: Novus Biologicals
Description: The ZNF140 Antibody from Novus Biologicals is a rabbit polyclonal antibody to ZNF140. This antibody reacts with human. The ZNF140 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (103287-374)
Supplier: Novus Biologicals
Description: The ZNF622 Antibody from Novus Biologicals is a rabbit polyclonal antibody to ZNF622. This antibody reacts with human, mouse. The ZNF622 Antibody has been validated for the following applications: Western Blot, Immunoprecipitation.


Catalog Number: (76116-196)
Supplier: Bioss
Description: CA12 (Carbonic anhydrase XII) is a zinc metalloenzyme that catalyzes the reversible hydration of carbon dioxide.


Catalog Number: (10102-052)
Supplier: Prosci
Description: ZNF192 belongs to the krueppel C2H2-type zinc-finger protein family and contains the conserved SCAN box domain. ZNF192 may be involved in transcriptional regulation.


Catalog Number: (10102-748)
Supplier: Prosci
Description: TRIM55 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described.


Catalog Number: (10104-858)
Supplier: Prosci
Description: SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of bone cell differentiation.


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