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Catalog Number: (89416-540)
Supplier: Prosci
Description: EVER1 Antibody: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance.


Catalog Number: (89416-542)
Supplier: Prosci
Description: EVER1 Antibody: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance.


Catalog Number: (10282-666)
Supplier: Bioss
Description: TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.


Supplier: Epredia
Description: Transport, store and retrieve pathology specimens in a safe and cost-effective manner.

SDS

Catalog Number: (10100-070)
Supplier: Prosci
Description: SMYD5 contains 1 MYND-type zinc finger and 1 SET domain. The exact function of SMYD5 remains unknown.


Catalog Number: (10469-602)
Supplier: Bioss
Description: This gene encodes for a coiled coil domain containing 16 protein and is located on chromosome 17. The protein may act as a regulator of the cell cycle in embryos by participating in control of M phase.


Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: pH adjusters are used to adjust the pH of formulations. This category includes acids that are notoriously difficult to source as truly cGMP-produced and amino acids that most companies do not fully test for EP, BP and JP. Avantor provides all that and more with our cGMP-produced acids and mutli-compendial amino acids.
Catalog Number: (10108-490)
Supplier: Prosci
Description: MBNL1 contains 4 C3H1-type zinc fingers and binds to CUG triplet repeat expansion dsRNA.


Catalog Number: (10105-504)
Supplier: Prosci
Description: The ZNF654 gene, located on chromosome 17, encodes a protein that is part of the zinc finger family.


Catalog Number: (76010-332)
Supplier: Prosci
Description: This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.


Catalog Number: (10255-126)
Supplier: Bioss
Description: GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.


Supplier: Action Pump
Description: Metal-body pumps for use in tight work areas where drums containing flammables are stored.

Catalog Number: (10461-532)
Supplier: Bioss
Description: ZNF420 contains 19 C2H2-type zinc fingers and 1 KRAB domain. It may be involved in transcriptional regulation. It is a negative regulator of p53-mediated apoptosis.


Catalog Number: (10749-104)
Supplier: Prosci
Description: The Makorin ring finger 3 (MKRN3) protein contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. The MKRN3 gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome , but a deletion of the gene does not. A deficiency of MKRN3 has been shown to cause central precocious puberty in humans.


Catalog Number: (10093-782)
Supplier: Proteintech
Description: RING finger (C3HC4-type zinc finger) is a variant zinc finger motif present in a new family of proteins including transcription regulators. RNF10 (RING finger protein 10), a 90-kDa protein, contains a ring finger motif which is known to be involved in protein-protein interactions. RNF10 regulates myelin-associated glycoprotein (MAG) expression and is required for myelin formation, therefore, participates in the peripheral nerve development and Schawnn cell differentiation. RNF10 is also involved in activation of p21WAF1 promoter via its activity as transcriptional factor.


Catalog Number: (10106-348)
Supplier: Prosci
Description: Located on chromosome 19, ZNF551 encodes a protein that is part of the zinc finger protein family.


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