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Catalog Number: (75789-482)
Supplier: Prosci
Description: CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules. The extracellular domain of CD99 contains no identifiable motifs, its cytoplasmic region, although short, does have signal transduction capability. Cells known to express CD99 include fibroblasts, neutrophils, T cells, double positive thymocytes, CD34+ stem cells, monocytes and endothelial cells. Two types of CD99 isoforms have been classified. Native human CD99 is referred to as the long, or type I isoform. The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 amino acids. The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II), and mediate clearly different biological outcomes. Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation. Human CD99 has 48% aa sequence identity to mouse CD99.


Catalog Number: (ABCA_AB216483-100U)
Supplier: ABCAM INC.
Description: Anti-TGF beta Receptor II Rabbit Polyclonal Antibody

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Catalog Number: (10332-654)
Supplier: Bioss
Description: Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.


Catalog Number: (470044-566)
Supplier: VWR
Description: With this Complete Sheep Heart Dissection Lab, you’ll receive: 10 high quality specimens that are easy to pin and dissect, packed in formaldehyde-free Borealene II. 20 student manuals with pre-test, post-test and easy to follow step-by-step instructions. 10 disposable dissection trays that offer direct pinning to the surface with no cleanup or resurfacing. Teacher’s guide with student objectives, teaching hints and answers to student tests. Replacement Student Manuals and Teacher’s Guides may also be purchased separately.

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Catalog Number: (10358-060)
Supplier: Bioss
Description: Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76% sequence identity and are 50% related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.


Supplier: Strem Chemicals Inc
Description: CAS #: 1315-09-9. Size: 25g.

Catalog Number: (76960-598)
Supplier: ANTIBODIES.COM LLC
Description: Recombinant rabbit monoclonal [TOP2A/4397R] antibody to Topoisomerase II alpha for IHC-P with samples derived from Human.


Supplier: Bel-Art Products
Description: Laboratory space is always in high demand making the small footprint of the Scienceware® Lab-Aire® II Drying Racks a practical solution for drying and storing fragile, frequently used labware.

Supplier: Biotium
Description: MHC II (HLA-DP), Monoclonal antibody, Clone: Bra-14, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Human REH cells, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL

Catalog Number: (10261-072)
Supplier: Bioss
Description: In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Binding of TFIID to the TATA element initiates assembly of the other factors into a pre-initiation complex. The TATA-binding subunit of TFIID (designated TFIIDt or TBP) from higher eukaryotes contains a highly conserved 180 amino acid C-terminal domain.


Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Powder. Lot analysis on label.
Supplier: BeanTown Chemical
Description: CAS: 7699-45-8; EC No: 231-718-4; MDL No: MFCD00011294; RTECS: ZH1150000 UN No: UN3260; Haz Class: 8; Packing Group: II Crystalline; Linear Formula: ZnBr2; MW: 225.19 Melting Point: 394°; Boiling Point: 697° Density (g/mL): 4.2; Refractive Index: 1.545 Moisture sensitive

SDS

Catalog Number: (77524-412)
Supplier: AFG BIOSCIENCE LLC
Description: Rat TGFbR2 (Transforming Growth Factor Beta Receptor II) ELISA Kit


Catalog Number: (77515-834)
Supplier: AFG BIOSCIENCE LLC
Description: Human TGFbR2 (Transforming Growth Factor Beta Receptor II) ELISA Kit


Supplier: Sartorius
Description: These MCE series advanced user interface balances have fully customizable hardware, software, and connectivity including touch, scroll, swipe functionality with factory-installed essential weighing applications and diverse QApp packages for optional software extension.

Catalog Number: (89358-300)
Supplier: Genetex
Description: CTR9, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and PAF1 (MIM 610506) form the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM]


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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