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Catalog Number: (102511-776)
Supplier: Adipogen
Description: Human MHC Class II (HLA-DP, DQ & DR) molecules are expressed on dendritic cells, monocytes, macrophages and myeloid beta cells. MHC Class II molecules are heterodimers of polymorphic transmembrane a and b chains and generally bind exogenously derived peptides of about 10-17 amino acids. MHC Class II molecules interact with the T cell receptor on CD4+ T cells.

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Supplier: Biotium
Description: This antibody recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.

Catalog Number: (102681-524)
Supplier: Electron Microscopy Sciences
Description: The Static Line II ionizer is an antistatic device which emits negative and positive ions, neutralizing the electrostatic charging in the cryochamber.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011295 Fieser: 1,1289 13,349 15,368 16,391 18,410 19,409 20,439 21,493
Catalog Number: (76109-470)
Supplier: Bioss
Description: Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence.


Catalog Number: (101094-902)
Supplier: USP
Description: (200 mg)

SDS


Catalog Number: (10138-070)
Supplier: PERKINELMER U.S. LLC
Description: This spares kit is designed for GemTip cross-flow nebulizers in Optima® 2x00/4x00/5x00/7x00 DV ICP-OES series instruments. It includes general replacement parts for the nebulizer.


Catalog Number: (10800-630)
Supplier: Rockland Immunochemical
Description: Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.


Catalog Number: (470327-384)
Supplier: ELEVATE HEALTHCARE, INC. SE
Description: Matches the acoustic characteristics of real tissue.


Supplier: Bon Opus Biosciences
Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Supplier: TCI America
Description: CAS Number: 14187-32-7 MDL Number: MFCD00005098 Molecular Formula: C20H24O6 Molecular Weight: 360.41 Purity/Analysis Method: <gt/>99.0% (GC) Form: Crystal Boiling point (°C): 382 Melting point (°C): 163
Catalog Number: (RL600-401-873)
Supplier: Rockland Immunochemical
Description: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 54 kDa in size corresponding to CaM Kinase II by western blotting.


Catalog Number: (10101-562)
Supplier: Prosci
Description: RFXAP is part of the RFX complex that binds to the X-box of MHC II promoters.Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


Supplier: BeanTown Chemical
Description: CAS: 12069-00-0; EC No: 235-109-4; MDL No: MFCD00016273 UN No: UN3077; Haz Class: 9; Packing Group: III 3-6mm Fused Lump; Molecular Formula: PbSe ; MW: 286.15 Density (g/mL): 8.1

SDS

Catalog Number: (89357-564)
Supplier: Genetex
Description: Rabbit polyclonal antibody to HLA-DRB1 (major histocompatibility complex, class II, DR beta 1)


Catalog Number: (76500-162)
Supplier: Janitorial Supplies
Description: Fast-acting formula penetrates and lifts dirt to deliver a total clean in the bathroom.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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