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Supplier: Spectrum Chemicals
Description: BSE/TSE statement (available upon request) Allergen statement (available upon request)
Supplier: MilliporeSigma
Description: EMSURE® (formerly GR) is a premium grade of reagents for wet chemical analysis, adhering to ACS, ISO, and/or Reag. Ph.Eur quality specifications.
Supplier: New England Biolabs (NEB)
Description: PaqCI is a Type IIS restriction enzyme with a 7 basepair recognition sequence: CACCTGC(⁴/₈).

Catalog Number: (75844-036)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.


Supplier: AMBEED, INC
Description: [(S,S)-Teth-TsDPEN-RuCl] ≥98%

New Product

Catalog Number: (10393-096)
Supplier: Bioss
Description: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface.


Supplier: TCI America
Description: [RuCl(p-cymene)((R)-tolbinap)]Cl, Cas: 1034001-51-8, MF: C58H54Cl2P2Ru, MW: 984.99, Synonyms: Chloro[(R)-(+)-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) Chloride, Appearance: Yellow - Deep reddish yellow solid crystal powder, Size: 1G

SDS

Supplier: Enzo Life Sciences
Description: A DNA-intercalating antitumor agent. Inhibits DNA topoisomerase II. Inhibits the phosphorylation of p53 in Lewis lung carcinoma cells and induces apoptosis. Inhibits cytochrome P-450-1A1.

Catalog Number: (76700-708)
Supplier: AFG BIOSCIENCE LLC
Description: Dog Insulin-like Growth Factor II(IGF2) ELISA Kit


Catalog Number: (76701-500)
Supplier: AFG BIOSCIENCE LLC
Description: Human Keratin, Type II Cytoskeletal 75(KRT75) ELISA Kit


Supplier: Biotium
Description: MHC II (HLA-DP), Monoclonal antibody, Clone: BRA-FB6, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Human REH cells, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL

Supplier: Biotium
Description: MHC II (HLA-DP), Monoclonal antibody, Clone: BRA-FB6, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Human REH cells, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL

Supplier: Bachem Americas
Description: The sequences given for angiotensin I (H-1680) and II (H-1705) correspond to the sequences of human, horse, sheep, pig, mouse, and rat angiotensins I and II.

Catalog Number: (77126-116)
Supplier: Prosci
Description: <i>P. falciparum</i> Recombinant Protein II Protein (from <i>E. coli</i>)


Catalog Number: (10337-692)
Supplier: Bioss
Description: Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.


Catalog Number: (103501-438)
Supplier: BioVendor
Description: The ENDONEXT™ EndoZyme® II assay is the enhanced second generation of EndoZyme®, based on recombinant Factor C (rFC), the synthetic analogue to the native endotoxin-specific principal receptor in the limulus amebocyte lysate (LAL) cascade.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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