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Catalog Number: (10670-778)
Supplier: Bioss
Description: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011300
Catalog Number: (10229-282)
Supplier: Bioss
Description: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.


Supplier: Upchurch Scientific
Description: RheFlex® M4x0.7 plugs are designed to seal off unused receiving ports in MX Series II high pressure valves

Catalog Number: (89354-924)
Supplier: Genetex
Description: Rabbit polyclonal antibody to PAF1 (PAF1, RNA polymerase II associated factor, homolog (S. cerevisiae))


Catalog Number: (10100-418)
Supplier: Prosci
Description: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. ARG2 (type II isoform) is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


Catalog Number: (76521-328)
Supplier: Beckman Coulter
Description: Class II Type biosafety containment cabinet designed specifically for the CytoFLEX SRT in collaboration with Baker Corporation, including aerosol evacuation functionality.


Catalog Number: (76708-012)
Supplier: AFG BIOSCIENCE LLC
Description: Human Keratin, Type II Cytoskeletal 1(KRT1) ELISA Kit


Catalog Number: (10468-492)
Supplier: Bioss
Description: Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4. hCAP-D3 is a regulatory non-SMC subunit of the condensin II complex.


Catalog Number: (10765-950)
Supplier: Prosci
Description: Rat Monoclonal MHC Class II Antibody [M5/114.15.2] (PE), Isotype: Mouse IgG1, kappa, Species: Human, Application: FACS


Catalog Number: (77525-086)
Supplier: AFG BIOSCIENCE LLC
Description: Simian IL1R2 (Interleukin 1 Receptor Type II) ELISA Kit


Catalog Number: (77528-196)
Supplier: AFG BIOSCIENCE LLC
Description: Guinea pig AGTR1 (Angiotensin II Receptor 1) ELISA Kit


Catalog Number: (76119-642)
Supplier: Bioss
Description: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. NCAPG2 is 1 of 3 non-SMC subunits that define condensin II. Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4, but they contain different sets of non-SMC subunits. NCAPG2 is 1 of 3 non-SMC subunits that defines condensin II.


Catalog Number: (10771-688)
Supplier: PeproTech, Inc.
Description: The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro . IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant Human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. The calculated molecular weight of Recombinant Human IGF-I is 7.6 kDa.


Supplier: Simport Scientific
Description: These patented cassettes keep specimens safely submerged in liquid and are totally resistant to the chemical action of histological solvents.

Catalog Number: (80050-774)
Supplier: MilliporeSigma
Description: A potent and reversible inhibitor of caspase-1 (ICE), caspase-3, caspase-4, and caspase-7.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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