You Searched For: Palladium+(II)+iodide

Catalog Number: (102511-778)

Supplier: Adipogen

Description: Human MHC Class II (HLA-DP, DQ & DR) molecules are expressed on dendritic cells, monocytes, macrophages and myeloid beta cells. MHC Class II molecules are heterodimers of polymorphic transmembrane a and b chains and generally bind exogenously derived peptides of about 10-17 amino acids. MHC Class II molecules interact with the T cell receptor on CD4+ T cells.

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Catalog Number: (102182-004)

Supplier: Novus Biologicals

Description: Mouse Monoclonal Hexokinase II Antibody (3D3). Tested Applications: Western Blot, ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin. Tested Reactivity: Human.

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Catalog Number: (103616-966)

Supplier: Sino Biological

Description: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human AIMP1 / EMAP II (rh AIMP1 / EMAP II; Catalog#10623-H07E; NP_004748.2; Ala2-Lys312). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

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Catalog Number: (ABCA_AB20184-50UG)

Supplier: ABCAM INC.

Description: Anti-HLA Class II DRB1 Mouse Monoclonal Antibody [clone: DA2]

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Catalog Number: (89286-082)

Supplier: Genetex

Description: Goat Polyclonal antibody to EMAP II (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1) Purity: Immunogen affinity purified Species Reactivity: Human Tested Applications: ELISA WB Pkg Size: 50 ug

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Catalog Number: (76101-652)

Supplier: Bioss

Description: Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

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Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00049743

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Catalog Number: (76705-116)

Supplier: AFG BIOSCIENCE LLC

Description: Human Decorin/Bone proteoglycan II (DCN) ELISA Kit

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Supplier: Ricca Chemical

Description: 220 g + 870 ml H₂O

SDS Certificates

Supplier: GENOSENSOR CORPORATION

Description: Your students are asked to identify the unknown predator that is killing calves on a nearby ranch.

Catalog Number: (10332-648)

Supplier: Bioss

Description: Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.

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Catalog Number: (76965-306)

Supplier: ANTIBODIES.COM LLC

Description: Recombinant rabbit monoclonal [TOP2A/4397R] antibody to Topoisomerase II alpha for IHC-P with samples derived from Human.

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Catalog Number: (10393-102)

Supplier: Bioss

Description: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface.

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Catalog Number: (102708-530)

Supplier: Novus Biologicals

Description: The Glyoxalase II / HAGH Antibody from Novus Biologicals is a rabbit polyclonal antibody to Glyoxalase II / HAGH. This antibody reacts with human. The Glyoxalase II / HAGH Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Supplier: THERMO FISHER SCIENTIFIC CHEMICALS

Description: EDTA (ethylenediamine tetraacetic acid) 99%, pure

Catalog Number: (89366-016)

Supplier: Genetex

Description: HLA Class II molecules are usually found on professional antigen presenting cells, such as macrophages, B cells and dendritic cells. These molecules play a crucial role in defending against extracellular pathogens.

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