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Catalog Number: (10234-468)
Supplier: Bioss
Description: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.


Catalog Number: (10235-808)
Supplier: Bioss
Description: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.


Catalog Number: (89356-762)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to Hexokinase II (hexokinase 2)


Supplier: MilliporeSigma

SDS

Catalog Number: (10670-776)
Supplier: Bioss
Description: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.


Catalog Number: (10670-772)
Supplier: Bioss
Description: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.


Catalog Number: (77521-416)
Supplier: AFG BIOSCIENCE LLC
Description: Mouse UQCRC2 (Ubiquinol Cytochrome C Reductase Core Protein II) ELISA Kit


Catalog Number: (18901-110)
Supplier: Brandtech
Description: For instruments with maximum capacities greater than 10mL. Not for use with Dispensette II, Dispensette Organic or Dispensette HF.


Supplier: Thermo Scientific Chemicals
Description: Grade: 98. Melting Point Cca 800*(dec). Boiling Point C: NA. C2N2Zn. 557-21-1. HIGHLY TOXIC DANGEROUS FOR THE ENVIRONMENT HYGROSCOPIC
Supplier: Honeywell Research Chemicals
Description: Ferroin indicator solution, Analytical, redox indicator, 0.025 M, CAS Number: 14634-91-4, Synonym: 1, 10-Phenanthroline iron(II) sulfate complex, o-Phenanthroline ferrous sulfate complex, Linear Formula: [Fe(C12H8N2)3]SO4, Indicator Reagent, Size: 250ML
Catalog Number: (89161-066)
Supplier: Enzo Life Sciences
Description: CaM kinase inhibitor


Catalog Number: (77746-689)
Supplier: AMBEED, INC
Description: Diacetato{(S)-(+)-5,5'-bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole}ruthenium(II) ≥98%

New Product


Catalog Number: (75789-694)
Supplier: Prosci
Description: Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.


Catalog Number: (ABCA_AB212444-100U)
Supplier: ABCAM INC.
Description: Anti-HLA Class II DRB1 Mouse Monoclonal Antibody [clone: LN-3]

New Product


Catalog Number: (102106-036)
Supplier: Novus Biologicals
Description: The RNA Polymerase II / POLR2A [p Ser2] Antibody from Novus Biologicals is a rabbit polyclonal antibody to RNA Polymerase II / POLR2A. This antibody reacts with human, mouse, yeast. The RNA Polymerase II / POLR2A [p Ser2] Antibody has been validated for the following applications: Western Blot, Immunoprecipitation, Immunohistochemistry-Paraffin, Proximity Ligation Assay.


Catalog Number: (76700-842)
Supplier: AFG BIOSCIENCE LLC
Description: Rat Coagulation factor II (FII) ELISA Kit


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