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Catalog Number: (89358-300)
Supplier: Genetex
Description: CTR9, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and PAF1 (MIM 610506) form the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM]


Catalog Number: (77439-766)
Supplier: Bioss
Description: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.


Supplier: Enzo Life Sciences
Description: CaM kinase II inhibitor

Supplier: Biotium
Description: MHC II (HLA-DP), Monoclonal antibody, Clone: Bra-14, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Human REH cells, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL

Catalog Number: (10332-652)
Supplier: Bioss
Description: Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.


Supplier: Strem Chemicals Inc
Description: CAS #: 1315-09-9. Size: 5g.

Catalog Number: (89235-046)
Supplier: Corning
Description: Synthemax® II-SC Substrate is an easy to use, self-coating material for creating a unique synthetic surface that mimics the natural cell environment. This surface supports the adhesion and expansion of stem cells in their undifferentiated state and directs differentiation into specialized cell types. In addition, it offers a synthetic, xeno-free alternative to biological coatings and/or feeder cell layers used in hES and iPS cell culture, whenever needed and appropriate.

Supplier: ACROBIOSYSTEMS
Description: Human TOP2A/TOP2 Protein, Tag Free, Source: expressed from E.coli cells. It contains AA Ser 1354 - Ser 1473, Predicted N-terminus: Met, protein carries no tag, Synonyms: TOP2A, TOP2, DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme, Size: 500uG

Supplier: American 3B Scientific
Description: Laser diode of protection classification II with 1 m connector lead and barrel connector for connecting ultrasonic cw generator.

Supplier: AMBEED, INC
Description: Manganese(II) disodium 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetate, Purity: 98%, CAS Number: 15375-84-5, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 1000G

Catalog Number: (10166-288)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to RAB11FIP4 (RAB11 family interacting protein 4 (class II))


Catalog Number: (75789-482)
Supplier: Prosci
Description: CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules. The extracellular domain of CD99 contains no identifiable motifs, its cytoplasmic region, although short, does have signal transduction capability. Cells known to express CD99 include fibroblasts, neutrophils, T cells, double positive thymocytes, CD34+ stem cells, monocytes and endothelial cells. Two types of CD99 isoforms have been classified. Native human CD99 is referred to as the long, or type I isoform. The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 amino acids. The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II), and mediate clearly different biological outcomes. Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation. Human CD99 has 48% aa sequence identity to mouse CD99.


Supplier: Thermo Scientific Chemicals
Description: UN3181,Powder, Packaged under argon,DANGER: FLAMMABLE, irritates skin, eyes, lungs,1g,5g,FLAMMABLE SOLID,
Catalog Number: (10090-082)
Supplier: Proteintech
Description: Mediator of RNA polymerase II transcription subunit 12 (MED12), also named Activator-recruited cofactor 240 kDa component, Thyroid hormone receptor-associated protein complex 230 kDa component. MED12 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. Molecular weight of MED12 is about 240kd.This antibody is specific to MED12.


Catalog Number: (77524-412)
Supplier: AFG BIOSCIENCE LLC
Description: Rat TGFbR2 (Transforming Growth Factor Beta Receptor II) ELISA Kit


Catalog Number: (77515-834)
Supplier: AFG BIOSCIENCE LLC
Description: Human TGFbR2 (Transforming Growth Factor Beta Receptor II) ELISA Kit


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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