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Catalog Number: (10234-454)
Supplier: Bioss
Description: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.


Catalog Number: (10234-466)
Supplier: Bioss
Description: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.


Supplier: AMBEED, INC
Description: Zinc stearate ZnO 12.5-14%

New Product

Catalog Number: (76709-310)
Supplier: AFG BIOSCIENCE LLC
Description: Horse Angiotensin II (ANG-Ⅱ) ELISA Kit


Catalog Number: (76707-134)
Supplier: AFG BIOSCIENCE LLC
Description: Rat Calcium/Calmodulin-dependent Protein Kinase-II (CAMK 2) ELISA Kit


Catalog Number: (RL200401136S)
Supplier: Rockland Immunochemical
Description: Carbonic Anhydrase II Antibody is suitable for western blotting, ELISA and IHC. Researchers should determine optimal titers for applications that are not stated below.


Catalog Number: (PAM7660)
Supplier: Promega Corporation
Description: Includes GoTaq DNA polymerase and PCR Nucleotide Mix, along with high-performance buffers and magnesium chloride. Core System II also includes a Positive Control Plasmid DNA and Positive Control Primers. Performance-tested in PCR.

Catalog Number: (10229-272)
Supplier: Bioss
Description: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.


Catalog Number: (10670-756)
Supplier: Bioss
Description: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.


Catalog Number: (76173-114)
Supplier: Boster Biological Technology
Description: Rabbit IgG polyclonal antibody for Synapsin-2(SYN2) detection. Tested with WB in Human;Mouse;Rat.


Catalog Number: (10670-774)
Supplier: Bioss
Description: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.


Catalog Number: (77519-114)
Supplier: AFG BIOSCIENCE LLC
Description: Human IGFIIE (Pro-Insulin Like Growth Factor II E-Peptide) ELISA Kit


Supplier: BeanTown Chemical
Description: CAS: 13820-41-2; EC No: 237-499-1; MDL No: MFCD00010885; RTECS: TP1840000 UN No: UN3288; Haz Class: 6.1; Packing Group: III Crystalline; Linear Formula: (NH4)2PtCl4; MW: 372.97 Melting Point: 140° (decomposes) Density (g/mL): 2.936 Hygroscopic

SDS

Supplier: Bon Opus Biosciences
Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Supplier: International Crystal Labs
Description: Zinc Sulfide (ZnS) is used as a transmission window for IR spectroscopy. Zinc Sulfide (ZnS) is or has been produced under the trademarks Cleartran® and Irtran® .

Minority or Woman-Owned Business Enterprise

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011300
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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