You Searched For: Monarch+RNA+Cleanup+Kits

Catalog Number: (89165-838)

Supplier: Enzo Life Sciences

Description: Bio-11-CTP (Biotin-11-cytidine-5’-triphosphate) can replace CTP for <i>in vitro</i> transcription reaction catalysed by T3, T7 or SP6 RNA polymerases.

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Catalog Number: (75792-872)

Supplier: Prosci

Description: RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

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Catalog Number: (10294-236)

Supplier: Bioss

Description: Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

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Catalog Number: (80055-488)

Supplier: MilliporeSigma

Description: Uridine-5''-triphosphate, Trisodium. (UTP, sodium). White solid. HYGROSCOPIC. Energy-rich precursor in the enzymatic biosynthesis of mononucleotide limits of DNA and RNA. A potent vasodilator. Induces contractile responses in some tissues.

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Supplier: AIRCLEAN SYSTEMS BE

Catalog Number: (10360-506)

Supplier: Bioss

Description: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.

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Catalog Number: (10106-390)

Supplier: Prosci

Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX50 is a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. DDX50 and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. DDX50 gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.

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Catalog Number: (470138-074)

Supplier: Wards

Description: This model of the HIV virus is enlarged millions of times to show the outer lipid membrane with protein structures and the internal nucleoproteins and contained RNA.

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Catalog Number: (10409-424)

Supplier: Bioss

Description: Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3.The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene.

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Catalog Number: (89357-948)

Supplier: Genetex

Description: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]

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Catalog Number: (10751-968)

Supplier: Prosci

Description: DIS3 Antibody: The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.

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Catalog Number: (77438-610)

Supplier: Bioss

Description: Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA.

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Catalog Number: (76482-816)

Supplier: AAT BIOQUEST INC

Description: The amine-modified uridine 5'-triphosphates (such as aminoallyl-UTP) can be used to produce amine-containing RNA by conventional enzymatic incorporation methods such as transcription, nick translation, random primed labeling, or PCR.

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Supplier: Spectrum Chemicals

Description: Ribonucleic Acid, also known as RNA, is a polymeric molecule and used in many biological roles including decoding, regulation, and expression of genes.

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Catalog Number: (75934-296)

Supplier: Rockland Immunochemical

Description: WDR61 (WD-repeat-containing protein 61), also known as SKI8 or REC14, is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (1,2). PAF1C is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1C (3,4).

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Catalog Number: (10465-890)

Supplier: Bioss

Description: MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family bind to RNA with specificity for C-rich pyrimidine regions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements.

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