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Supplier: Anaspec Inc

Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is an exceptional MMP-2 (gelatinase A) and MMP-9 (gelatinase B) substrate: this peptide is used for the continuous spectrophotometric assay of MMP-2 and MMP-9 in combination with a color-developing thiol-reactive agent, 4,4’-dithiodipyridine or Ellman’s Reagent (as indicators). This thiol peptide-enzyme reaction has a Km of 0.004 M and a kcat of 103 s-1. Using this substrate, collagenase can be detected at concentrations as low as 2 ng/mL. HPLC and tandem mass spectrometry are also used to analyze MMP-2 and MMP-9 in conjunction with this peptide substrate.
Sequence:Ac-PLG-SCH[CH2CH(CH3)2]-CO-LG-OC2H5
MW:655.9 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (EM-SX0143J-3)

Supplier: MilliporeSigma

Description: Meets ACS Specifications

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Supplier: Shenandoah Biotechnology

Description: Myostatin (GDF-8), a member of the TGF-beta superfamily, is a potent and negative regulator of skeletal muscle mass. The recombinant myostatin propeptide binds and inhibits myostatin to enhance the repair and regeneration of injured muscle and bone.

Supplier: Honeywell Research Chemicals

Description: TraceSELECT™ Ultra and TraceSELECT

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Catalog Number: (10090-302)

Supplier: Proteintech

Description: MMP26(matrix metallopeptidase 26) may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor.MMP26 is expressed in placenta and uterus and is widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines.The proenzyme without the signal peptide has a calculated molecular mass of 29 KDa and the processed enzyme has a calculated molecular mass of 19KDa.This antibody is specific to MMP29.

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Catalog Number: (470303-846)

Supplier: Vernier Software & Technology

Description: Designed for use in situations in which low thermal mass or flexibility is required, the Go Direct Surface Temperature Sensor connects wirelessly via Bluetooth® or wired via USB to your device.

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Catalog Number: (MSPP-65-0001)

Supplier: PEAK SCIENTIFIC MS

Description: Peak Scientific’s Solaris 10 Nitrogen generator has been developed to provide an optimal gas generation solution for ELSD or Compact Mass Spectrometers, with the goal of reducing instrument downtime and improving workflow efficiencies.

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Supplier: Bon Opus Biosciences

Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Supplier: Honeywell Research Chemicals

Description: High purity Water; suitable for LC-MS applications and spectrophotometry. Contains no preservative.

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Catalog Number: (76243-440)

Supplier: ITW Chemtronics

Description: Soder-Wick® Rosin Flux Desoldering Braid is designed for heat sensitive electronic components using lighter mass, pure copper braid construction that allows for better thermal conductivity, even at low temperatures.

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Supplier: Bon Opus Biosciences

Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Supplier: Bachem Americas

Description: Sequence: Pyr-OH

Supplier: PeproTech, Inc.

Description: Sclerostin, a glycoprotein predominantly secreted by osteocytes, is a member of the Cerberus/DAN family of putative BMP antagonists that functions as an endogenous regulator of the canonical Wnt signaling pathway and an inhibitory regulator of bone homeostasis. Although expressed nearly exclusively by osteocytes, sclerostin can also be found at significant levels elsewhere, such as bone, bone marrow, cartilage, the kidney, and the liver, and has also been shown to be produced by hypertrophic chondrocytes and cementocytes. Like DKK family members DKK-1 and DKK-4, sclerostin plays an important regulatory role in the Wnt/beta-catenin signaling pathway by forming inhibitory complexes with LDL Receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/beta-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/beta-catenin signaling cascade. Sclerostin has also been shown to interact directly with LRP4 via its extracellular domain to facilitate inhibition of Wnt signaling, and can catabolically promote osteoclast activity by increasing osteocyte expression of RANKL. Sclerostin's critical involvement in the regulation of bone formation and resorption is emphasized by two bone dysplasia disorders, sclerosteosis and van Buchem disease (VBD), caused by rare autosomal recessive mutations that result in progressive bone overgrowth and hypermineralization due to markedly decreased sclerostin levels. PeproTech's CHO cell-derived Recombinant Human Sclerostin is a 190-amino-acid-length glycoprotein with a calculated molecular weight of 21.5 kDa. As a result of glycosylation, Recombinant Human Sclerostin migrates with an apparent molecular mass of approximately 28-35 kDa by SDS-PAGE gel, under non-reducing conditions.

Catalog Number: (BJLC583-4)

Supplier: Honeywell Research Chemicals

Description: LabReady™ Solvent Blends

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Catalog Number: (10081-296)

Supplier: Proteintech

Description: ENTPD8(Ectonucleoside triphosphate diphosphohydrolase 8) is also named as E-NTPDase 8, NTPDase8 and belongs to the GDA1/CD39 NTPase family. NTPDase8 is the canalicular ecto-ATPase/ATPDase and is responsible for the main hepatic NTP-Dase activity. The estimated molecular mass of expressed human E-NTPDase 8 is 70-85 kDa which is N-glycosylated and after deglycosylation,it has a nearly identical molecular mass, 54 kDa. It has 2 isoforms produced by alternative splicing with the molecular weight of 54 kDa and 49 kDa. This antibody is specific to ENTPD8.

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Supplier: Electron Microscopy Sciences

Description: This graticule consists of a number of short lines with interruptions as long as the lines.