You Searched For: Stability chamber

Description: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 alpha chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cell express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: 75980-566

Supplier: Biotium

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Description: Vimentin, Monoclonal antibody, Clone: VM1170, Host: Mouse, Species reactivity: Mouse, Pig, Cow, Cat, Sheep, Rat, Human, Rabbit, Isotype: IgM, Conjugate: purified, Immunogen: Human thymic nuclear extract, Synonyms: VIM, Application: IF, Size: 500uL

Catalog Number: 75979-382

Supplier: Biotium

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Description: is prepared by labeling IgG w/CF568, red fluorescent dye w/an excitation spectrum optimal for 568nm laser line. Antibody conjugates of the dye are brighter & more photostable than Alexa Fluor 568 making CF568 a better choice for demanding applications.

Catalog Number: 89138-548

Supplier: Biotium

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Description: PGP9.5 (UCHL-1), Monoclonal antibody, Clone: UCHL1/841, Host: Mouse, Species reactivity: Zebrafish, Pig, Dog, Cow, Sheep, Rat, Human, Rabbit, Isotype: IgG2a, kappa, Conjugate: CF647, Immunogen: Native UchL1 (PGP9.5) protein from brain, Application: IF, Size: 100uL

Catalog Number: 75969-986

Supplier: Biotium

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Description: TNF alphA, Monoclonal antibody, Clone: TNF655, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recombinant human TNF-alpha, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Catalog Number: 75976-994

Supplier: Biotium

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Description: TGF-alpha, Monoclonal antibody, Clone: MF9, Host: Mouse, Species reactivity: Rabbit, Zebrafish, Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: A 10-amino acid synthetic peptide (aa34-43), Synonyms: EGF-like TGF; ETGF, Application: IF, Size: 100uL

Catalog Number: 75975-290

Supplier: Biotium

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Description: KBA.62 is a novel anti-melanoma antibody. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, it reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. KBA.62 antibody is useful in identifying malignant melanomas. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, sarcomas, spindle cell carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immuno-reacts with antibody to S-100 protein and with KBA.62 antibody is, with rare exception, a melanoma. Anti-KBA.62 is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases and in the context of micro-metastasis in sentinel lymph node.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: 75960-334

Supplier: Biotium

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Description: This antibody recognizes human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: 75913-966

Supplier: Biotium

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Description: This MAb recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSF's, which are identical except for a three amino acid deletion in the amino-terminus of one form of the protein have been isolated from human cells. Murine and human G-CSF's share 73% sequence identity at the amino acid level.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: 75927-412

Supplier: Biotium

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Description: This antibody recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: 75972-326

Supplier: Biotium

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Description: Kits to detect live and dead bacteria, and perform Gram stain using fluorescent wheat germ agglutinin (WGA) conjugate.

Catalog Number: 89260-218

Supplier: Biotium

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Description: Live-or-Dye NucFix™ Red is a red fluorescent dye to covalently label dead cells, allowing cells with permeable plasma membranes to be detected by flow cytometry or fluorescence microscopy.

Catalog Number: 75832-822

Supplier: Biotium

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Description: This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Catalog Number: 75959-858

Supplier: Biotium

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Description: Goat anti-mouse IgG2b is an affinity-purified antibody that reacts with Fc portion of the heavy chain of mouse IgG2b. To minimize cross reactivity, the antibody is cross-adsorbed against other mouse IgG subclasses (IgG1, IgG2a, IgG3), and human, bovine and rabbit serum proteins. CF™405S is a blue fluorescent dye with an absorption peak wavelength that nearly coincides with the 405 nm blue diode laser line. In addition, the emission peak wavelength of the dye well centers within the blue detection window of BD flow cytometers. As a result, flow cytometry analysis using CF™405S results in much brighter signal compared to Alexa Fluor® 405.

Alexa Fluor® is a registered trademark of Thermo Fisher Scientific.

Catalog Number: 10018-288

Supplier: Biotium

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Description: Napsin-A, Monoclonal antibody, Clone: NAPSA/1239, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF405S, Immunogen: Recombinant fragment of human Napsin-A protein, Synonyms: ASP4, Aspartyl protease 4, KAP, NAP1, NAPA, Application: IF, IHC, WB, Size: 500uL

Catalog Number: 75965-520

Supplier: Biotium

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Description: Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10 + VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Size: 500uL

Catalog Number: 75979-128

Supplier: Biotium

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