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Catalog Number: (10399-456)
Supplier: Bioss
Description: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.


Catalog Number: (10399-452)
Supplier: Bioss
Description: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.


Catalog Number: (10399-398)
Supplier: Bioss
Description: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.


Catalog Number: (10407-090)
Supplier: Bioss
Description: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.


Catalog Number: (10200-150)
Supplier: Thermo Scientific
Description: This compact microbiological incubator's extremely small footprint makes it ideal for a personalized workspace or crowded labs with small sample volumes.

Product available on GSA Advantage®


Supplier: CT International
Description: PFXT series are class 100 powder free gloves.

Catalog Number: (10116-266)
Supplier: Prosci
Description: Polyclonal antibody Mammaglobin A Host: Goat immunogen: Mammaglobin A antibody was raised against a 12 amino acid synthetic peptide near the internal region of Mammaglobin A. Application: ELISA IHC


Supplier: Globe Scientific
Description: Produced from polypropylene, cap inserts are available in assorted colors and are ideal for color coding and sample identification

Catalog Number: (10097-022)
Supplier: Proteintech
Description: VPS37A, also named as HCRP1, belongs to the VPS37 family. It is a regulator of vesicular trafficking process. VPS37A is a member of the endosomal sorting complex required for transport (ESCRT) system, in upper motor neuron disease. ESCRT has been shown to play a central role in intracellular trafficking, in the maturation of multivesicular bodies and the sorting of ubiquitinated membrane proteins into internal luminal vesicles.


Catalog Number: (10281-922)
Supplier: Bioss
Description: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity).


Catalog Number: (21022-760)
Supplier: Corning
Description: These heavy duty 40 ml PYREX® conical centrifuge tubes are made with increased wall thickness for greater mechanical strength.

Catalog Number: (470150-578)
Supplier: ROLF C. HAGEN (USA) CORP.
Description: Excellent filtration inside the tank!


Catalog Number: (10116-600)
Supplier: Prosci
Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: Rhophilin 2 antibody was raised against an 11 amino acid synthetic peptide near the internal region of Rhophilin 2; Application: ELISA, IHC


Catalog Number: (10756-144)
Supplier: EMI - Emergency Medical International
Description: The Vision™ with its 60 lumens of LED light gives you hands free lighting instantly


Supplier: BURKLE INC
Description: The sturdy forceps are ideal for use in laboratories.

Catalog Number: (10498-200)
Supplier: Genscript
Description: THE™ DYKDDDDK tag antibody [iFluor 488], mAb, mouse recognizes N-terminal, internal and C-terminal flag-tagged proteins.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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