You Searched For: Huckert\'s+International

Catalog Number: (470061-810)

Supplier: INTERNATIONAL VIDEO & ELECTRONICS

Description: The International DS-1000 Diamond Series 1000 Watt Type 3 Voltage converters offer best in class performance in voltage transformers. They are thoroughly tested to be free of defects in workmanship and materials and hand soldering insures to meet U.S Military specifications.

Sale

Catalog Number: (76277-114)

Supplier: EFD INC.- CUSTOMER SERVICE TE

Description: The 781S Series Low Volume Low Pressure (LVLP) spray systems apply consistent coatings of low- to medium-viscosity fluids exactly where needed.

Sale

Catalog Number: (89495-076)

Supplier: Genscript

Description: GenScript THE™ DYKDDDDK Tag antibody [FITC], mAb, Mouse recognizes C-terminal, N-terminal and internal DYKDDDDK tagged fusion proteins.

Sale

Catalog Number: (10239-800)

Supplier: Bioss

Description: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes SRC-dependent phosphorylation of the matrix protease MMP14 and its lysosomal degradation. FGFR4 signaling is down-regulated by receptor internalization and degradation; MMP14 promotes internalization and degradation of FGFR4. Mutations that lead to constitutive kinase activation or impair normal FGFR4 inactivation lead to aberrant signaling.

Sale

Catalog Number: (76262-968)

Supplier: Rockland Immunochemical

Description: ERK2 antibodies detect the ERK2 isoform. Mitogen activiated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Sale

Catalog Number: (76262-836)

Supplier: Rockland Immunochemical

Description: ERK2 antibodies detect the ERK2 isoform. Mitogen activiated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Sale

Catalog Number: (10084-286)

Supplier: Proteintech

Description: CD1A is an antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface. CD1A is a 50kd glycoprotein. It has a HeteroDimer form with MW 65-70kd.

Sale

Catalog Number: (10315-252)

Supplier: Bioss

Description: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.

Sale

Supplier: AZENTA US, INC

Description: Azenta Life Sciences 2D coded tubes provide a lifelong and secure chain of custody for samples in biobanks, compound libraries and a broad range of biological and chemical stores, including cryogenic storage.

Supplier: Metro

Description: For use with Super Erecta* and Super Erecta Super Adjustable wire shelving systems. Circular grooves at 2.5cm intervals, a double groove every 20.3cm, numbers at 5.1cm intervals. Height: 87.6cm. Height includes leveling bolt and cap.

Catalog Number: (76028-248)

Supplier: Berkshire

Description: The Cleanroom Flat Mop Cart is made of high quality stainless steel and is fully autoclavable

Sale

Catalog Number: (76509-294)

Supplier: Hardy Diagnostics

Description: Support stand provides stability and safety when positioning MULTIFLEX instruments to best capture laminar flow.

Sale

Catalog Number: (10730-410)

Supplier: Abnova

Description: Goat polyclonal antibody raised against synthetic peptide of PSMB4.

Sale

Catalog Number: (75834-228)

Supplier: Restek

Description: Kit contains

Sale

Catalog Number: (75933-644)

Supplier: Rockland Immunochemical

Description: The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and –B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5).

Sale

Supplier: GSC International

Description: These wide-mouth flint glass jars come with phenolic lids.