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Lipopolysaccharides (from E.coli) ≥99.9%, TLRpure, sterile

Supplier: Adipogen
Description: Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid differentiation protein 2 (MD-2). According to current consensus activation of TLR4 is preceded by the transfer of LPS to membrane-bound (m) or soluble (s) CD14 by LPS-binding protein (LBP). Re-form LPS and lipid A, but not S-form LPS, are capable of inducing TNF-alpha responses also in the absence of CD14. LPS, synthesized by most wild-type (WT) Gram-negative bacteria (S-form LPS), consists of three regions, the O-polysaccharide chain, which is made up of repeating oligosaccharide units, the core oligosaccharide and the lipid A, which harbors the endotoxic activity of the entire molecule. R-form LPS synthesized by the so-called rough (R) mutants of Gram-negative bacteria lacks the O-specific chain. Furthermore, the core-oligosaccharide may be present in different degrees of completion, depending on the class (Ra to Re) to which the mutant belongs. LPS are amphipathic molecules whose hydrophobicity decreases with increasing length of the sugar part. Based upon these differences, S- and R-form LPS show marked differences in the kinetics of their blood clearance and cellular uptake as well as in the ability to induce oxidative burst in human granulocytes and to activate the host complement system.

Product Image-89136-165

Corning® DeckWorks™ Barrier Pipette Tips, Hinged Rack, Corning

Supplier: Corning
Description: These low binding barrier tips feature an inert, high-density PE barrier to eliminate aerosol carryover contamination during critical pipetting procedures. The tips will not trap liquids or inhibit PCR in the event of over pipetting.

Certificates Environmentally Preferable Product available on GSA Advantage®

Product Image-10015-662

Sklarcut™ Metzenbaum-Lahey Dissecting Scissors, OR Grade, Sklar®

Catalog Number: (10015-662)
Supplier: Sklar
Description: Sklarcut™ Metzenbaum-Lahey Dissecting Scissors are used for dissecting and cutting tissue only.
Product Image-10196-416

Hildebrandt Uterine Hemostatic Forceps, OR Grade, Sklar

Catalog Number: (10196-416)
Supplier: Sklar
Description: Hildebrandt Uterine Hemostatic Forceps are industry standard.
Product Image-76202-464

LB Agar Medium Large Capsules, MP Biomedicals

Catalog Number: (76202-464)
Supplier: MP Biomedicals
Description: Rich medium for the growth of <i>E. coli</i> and certified for plasmid and other bacterial cultures in liquid medium.

Certificates


Product Image-10185-536

Teat Tumor Extractor, OR Grade, Sklar

Supplier: Sklar
Description: Merit™ Teat Tumor Extractor 4.5mm is a reusable, nickel plated stainless steel, physician grade instrument.

Product Image-10034-876

Whatman™ Mixed Cellulose Ester Membranes, Non-Sterile, 3 µm, Whatman Products (Cytiva)

Supplier: GE Healthcare - Whatman
Description: Whatman mixed cellulose ester membranes are composed of cellulose acetate and cellulose nitrate. These membranes are characterized by a smoother and more uniform surface than pure nitrocellulose filters.

SDS Certificates Product available on GSA Advantage®

Product Image-76192-614

Econo™ Lorna-Edna Towel Clamp, Floor Grade, Sklar®

Supplier: Sklar
Description: Econo™ Lorna (Edna) Towel Clamps are a non-perforating clamp used to secure instruments, surgical materials such as tubing, and towels to the drape surrounding a surgical site.

Image Unavailable-100190-782

Histidine/Biotin solution 0.5 mM, sterile

Catalog Number: (100190-782)
Supplier: MOLTOX Molecular Toxicology
Description: Histidine/Biotin solution is used for the genetic toxicity assays with emphasis on microbial mutagenicity.
Product Image-10184-376

Schroeder Vulsellum Forceps, OR Grade, Sklar

Supplier: Sklar
Description: Schroeder Vulsellum Forceps are industry standard.

Product Image-10195-190

TC Wangensteen Needle Holder, OR Grade, Sklar`

Catalog Number: (10195-190)
Supplier: Sklar
Description: TC Wangensteen Needle Holders are constructed of Tungsten Carbide and stainless steel
Product Image-10195-704

Herrick Kidney Clamp, OR Grade, Sklar®

Catalog Number: (10195-704)
Supplier: Sklar
Description: Herrick Kidney Clamps are Stainless Steel and Industry Standard.
Product Image-10184-618

Surgi-OR™ Russian Forceps, Mid-Grade, Sklar

Supplier: Sklar
Description: Surgi-OR™ Russian Forceps are medium-heavy forceps used for grasping heavy or thick tissue

Image Unavailable-76221-864

Human Recombinant MAP2K2

Catalog Number: (76221-864)
Supplier: Rockland Immunochemical
Description: MEK2 pS222-pS226 human recombinant control protein
Product Image-95016-746

Sephadex™ G-10 Gel Filtration Media, Cytiva

Supplier: GE Healthcare - Life Sciences
Description: Sephadex G-10 is a well established gel filtration medium for desalting and buffer exchange of peptides and small biomolecules >700 molecular weight.

SDS Certificates Product available on GSA Advantage®

Product Image-89214-348

Corning® Preassembled Closed Systems Solution Centrifuge Tubes, 50 ml, with Accessory, Corning

Catalog Number: (89214-348)
Supplier: Corning
Description: Corning® 50 ml PP preassembled closed systems solution centrifuge tubes, self-standing, with accessory.

Certificates Environmentally Preferable Product available on GSA Advantage®


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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