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Catalog Number: (470148-928)
Supplier: Shiv Dial Sud & Sons
Description: This apparatus makes it easy for students to learn about Boyle's Law.


Catalog Number: (76183-742)
Supplier: Safety & Industrial Supplies
Description: Durable sanded hardwood block and steel bristles are ideal for removing dirt and rust from pipe threads, welds, and metals.


Catalog Number: (102162-086)
Supplier: Novus Biologicals
Description: Mouse Monoclonal Integrin beta 3 Antibody (PM6/13). Tested Applications: Western Blot, Blocking/Neutralizing, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunop


Catalog Number: (76101-912)
Supplier: Bioss
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.


Catalog Number: (77439-634)
Supplier: Bioss
Description: Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with COMMD1 and promotes its 'Lys63'-linked polyubiquitination. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development.


Catalog Number: (102643-518)
Supplier: Jackson Immunoresearch Lab
Description: Bovine Serum Albumin (BSA) is used extensively as a carrier protein to dilute antibodies and as a general blocking agent in immunoassays and immunodetection protocols.
IgG-free BSA, which is also protease-free, alleviates many of the problems that contaminating IgG can cause.


Catalog Number: (10764-412)
Supplier: Prosci
Description: The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.


Catalog Number: (10663-892)
Supplier: Bioss
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008].


Supplier: Bio X Cell
Description: InVivoPlus human IgG2 isotype control, Clone: n/a, Isotype: human IgG2, Applications: in vivo blocking of PD-1/PD-L signaling, in vitro PD-1 neutralization, Immunohistochemistry (frozen), Flow cytometry, Western blot

Catalog Number: (102214-218)
Supplier: Novus Biologicals
Description: MTR Peptide. Tested Applications: Blocking/Neutralizing. Tested Reactivity: Non-species specific.


Catalog Number: (89420-338)
Supplier: Prosci
Description: NALP3 peptide is used for blocking the activity of NALP3 antibody.


Catalog Number: (89420-724)
Supplier: Prosci
Description: NOD6 peptide is used for blocking the activity of NOD6 antibody.


Catalog Number: (89420-732)
Supplier: Prosci
Description: NALP7 peptide is used for blocking the activity of NALP7 antibody.


Catalog Number: (89420-814)
Supplier: Prosci
Description: PEAR1 peptide is used for blocking the activity of PEAR1 antibody.


Catalog Number: (89420-480)
Supplier: Prosci
Description: ZSCAN4 pepide is used for blocking the activity of ZSCAN4 antibody.


Catalog Number: (89420-422)
Supplier: Prosci
Description: PICALM peptide is used for blocking the activity of PICALM antibody.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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