You Searched For: Heat+Block

Catalog Number: (PAP6711)

Supplier: Promega Corporation

Description: HaloTag Ligand Building Blocks are designed for use with HaloTag fusion proteins and can carry a variety of functionalities, including fluorescent labels, affinity tags and attachments to a solid phase.

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Catalog Number: (69100-003)

Supplier: Magid Glove

Description: Made from a standard weight cotton and polyester blend, the magid Greyt shadow guard GT955R/GT955RM loops-in terrycloth machine knit glove offers good thermal protection and strong cut and abrasion resistance with form-fitting comfort.

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Catalog Number: (500032-472)

Supplier: Janitorial Supplies

Description: Dissolves as it cleans the bowl and blues the water.

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Catalog Number: (89421-272)

Supplier: Prosci

Description: TMEM106B peptide is used for blocking the activity of TMEM106B antibody.

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Supplier: Justrite

Description: Going beyond protection and compliance, AccuFlow™ Type II Safety Cans provide fast, precision pouring when handling flammable liquids. Patented, innovative manifold automatically vents for smooth, glug-free liquid flow, while the comfortable Safe-Squeeze® trigger offers maximum control when pouring. A 9" (229mm) flexible metal hose offers targeted pouring into small openings. Quick-fill port with ergonomically designed lever handle makes filling easier than ever. Protection features include a long lasting, stainless steel flame arrester that dissipates heat to prevent flashback ignition and a gasketed, self-closing leakproof that automatically vents to guard against rupture or explosion. Warning label with extra large ID zone permits user to identify contents, department location, or individual user name. All can sizes have extra capacity for mixing in additives for two cycle engines.

Catalog Number: (10338-966)

Supplier: Bioss

Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]

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Catalog Number: (76078-534)

Supplier: Bioss

Description: BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70?s anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAGheterodimerization.

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Catalog Number: (89420-988)

Supplier: Prosci

Description: SPT2 peptide is used for blocking the activity of SPT2 antibody.

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Catalog Number: (89420-396)

Supplier: Prosci

Description: PPAPDC2 peptide is used for blocking the activity of PPAPDC2 antibody.

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Catalog Number: (89420-818)

Supplier: Prosci

Description: STOX2 peptide is used for blocking the activity of STOX2 antibody.

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Catalog Number: (89420-308)

Supplier: Prosci

Description: RWDD3 peptide is used for blocking the activity of RWDD3 antibody.

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Catalog Number: (89418-754)

Supplier: Prosci

Description: TRAF6 peptide is used for blocking the activity of TRAF6 antibody.

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Catalog Number: (89421-090)

Supplier: Prosci

Description: DPAGT1 peptide is used for blocking the activity of DPAGT1 antibody.

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Catalog Number: (89420-970)

Supplier: Prosci

Description: ATP2C1 peptide is used for blocking the activity of ATP2C1 antibody.

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Catalog Number: (89420-778)

Supplier: Prosci

Description: PLAC1 peptide is used for blocking the activity of PLAC1 antibody.

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Supplier: Enzo Life Sciences

Description: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

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