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Supplier: Enzo Life Sciences
Description: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

Catalog Number: (76481-712)
Supplier: AAT BIOQUEST INC
Description: FMOC-Asp(5-TAMRA)-OH is a building block for in-sequence peptide Asp labeling by TAMRA.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (76485-234)
Supplier: AAT BIOQUEST INC
Description: FMOC-Lys(QSY-21)-OH is a building block for in-sequence Lys labeling by QSY-21.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (89420-904)
Supplier: Prosci
Description: SLAMF9 peptide is used for blocking the activity of SLAMF9 antibody.


Catalog Number: (89420-692)
Supplier: Prosci
Description: WDR35 peptide is used for blocking the activity of WDR35 antibody.


Catalog Number: (103008-080)
Supplier: Anaspec Inc
Description: The synthetic peptide (Tat-Glur23Y) contains tyrosine residues that blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Previous research shows that Tat-Glur23Y blocks regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.
Sequence: YGRKKRRQRRRYKEGYNVYG
MW: 2634 Da
% Peak area by HPLC: 95
Storage condition: -20°C


Catalog Number: (76481-740)
Supplier: AAT BIOQUEST INC
Description: FMOC-Lys(5-TAMRA)-OH is a building block for in-sequence Lys labeling by TAMRA.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Supplier: Desco
Description: Statfree Z2™ Dissipative 3-Layer Vinyl Mats provide reliable path to ground and eliminate static charge.

Product available on GSA Advantage®

Supplier: Electron Microscopy Sciences

Catalog Number: (10317-806)
Supplier: Bioss
Description: HEATR8.


Catalog Number: (76437-110)
Supplier: Environmental Express
Description: Disposable digestion cups eliminate transfer steps.


Catalog Number: (10316-320)
Supplier: Bioss
Description: HEATR7A.


Catalog Number: (89418-932)
Supplier: Prosci
Description: The peptide is used for blocking the activity of the avian influenza neuraminidase antibody.


Catalog Number: (89420-298)
Supplier: Prosci
Description: Prosapip1 peptide is used for blocking the activity of Prosapip1 antibody.


Catalog Number: (89418-796)
Supplier: Prosci
Description: ILPIP peptide is used for blocking the activity of the ILPIP antibody.


Catalog Number: (89418-752)
Supplier: Prosci
Description: IRAK4 peptide is used for blocking the activity of IRAK-4 antibody.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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