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Aqua Block™ PBS

Supplier: Arlington Scientific
Description: A non-mammalian blocking reagent supplied in PBS for diagnostic systems involving membrane or other solid phase material.

Image Unavailable-103254-748

AdvanBlock™-PF Blocking Solution, Advansta

Catalog Number: (103254-748)
Supplier: ADVANSTA INC MS
Description: Non-protein blocking solution for fluorescent and chemiluminescent Western blotting
Image Unavailable-75812-448

Sodium hydroxide ≥95.0%, pellets NF

Supplier: Spectrum Chemicals
Description: Sodium Hydroxide, Pellets, NF is used as a pH adjusting agent. 

Certificates

Product Image-10108-168

Anti-SF3B1 Rabbit Polyclonal Antibody

Catalog Number: (10108-168)
Supplier: Prosci
Description: SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.
Image Unavailable-10289-264

Anti-DNAJC9 Rabbit Polyclonal Antibody

Catalog Number: (10289-264)
Supplier: Bioss
Description: The DnaJ family comprises a group of chaperone proteins that contain a J domain and have diverse cellular localization and functions. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis and are also important mediators of proteolysis and protein degradation. DnaJC9 (DnaJ (Hsp40) homolog, subfamily C, member 9), also designated HDJC9, JDD1 or DnaJ protein SB73, is a 260 amino acid protein found at moderate levels in most tissues with highest expression in the germinal zone of the central nervous system, testis, ovary, renal cortex and fetal liver. A member of the DnaJ family, DnaJC9 contains one N-terminal J domain but lacks the typical G/F and zinc finger regions that are typical of DnaJ family members. DnaJC9 localiizes to nuclei under normal conditions but may be transported to cytoplasm and plasma membrane when exposed to heat shock.
Image Unavailable-10240-674

Anti-HSPB1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10240-674)
Supplier: Bioss
Description: Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli. A major function of these proteins is to serve as chaperones that bind to and stabilize the active conformation of other proteins. HSP27, along with other members of the small HSP group, possesses a C-terminal Alpha-crystalline homology domain. HSP27 is localized to the cytoplasm of unstressed cells but can redistribute to the nucleus in response to stress, where it may function to stabilize DNA and/or the nuclear membrane. Cytoplasmic HSP27 exists in multiple complexes. One complex consists of HSP27, Akt (PKB), MAPKAP-kinase 2, and p38 MAPK. The presence of HSP27 in this complex is required for Akt activation by stress stimuli. Another complex consists of HSP27 and the IKK complex. HSP27 is also an actin capping protein that binds to the barbed (growing) ends of actin filaments, thereby inhibiting filament extension. Phosphorylation of HSP27 on serine 82 by MAPKAP-kinase 2 leads to HSP27 dissociation from the Akt/MAPKAP-kinase 2/p38 complex and from actin filaments, and stimulates HSP27 binding to the IKK complex.
Image Unavailable-10240-668

Anti-HSPB1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10240-668)
Supplier: Bioss
Description: Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli. A major function of these proteins is to serve as chaperones that bind to and stabilize the active conformation of other proteins. HSP27, along with other members of the small HSP group, possesses a C-terminal Alpha-crystalline homology domain. HSP27 is localized to the cytoplasm of unstressed cells but can redistribute to the nucleus in response to stress, where it may function to stabilize DNA and/or the nuclear membrane. Cytoplasmic HSP27 exists in multiple complexes. One complex consists of HSP27, Akt (PKB), MAPKAP-kinase 2, and p38 MAPK. The presence of HSP27 in this complex is required for Akt activation by stress stimuli. Another complex consists of HSP27 and the IKK complex. HSP27 is also an actin capping protein that binds to the barbed (growing) ends of actin filaments, thereby inhibiting filament extension. Phosphorylation of HSP27 on serine 82 by MAPKAP-kinase 2 leads to HSP27 dissociation from the Akt/MAPKAP-kinase 2/p38 complex and from actin filaments, and stimulates HSP27 binding to the IKK complex.
Image Unavailable-77321-628

Accessories for ThermoStat C

Supplier: Eppendorf
Description: Accessories for ThermoStat C

Environmentally Preferable

Image Unavailable-10088-516

Anti-HSPA2 Rabbit Polyclonal Antibody

Catalog Number: (10088-516)
Supplier: Proteintech
Description: Human HSPA2 is a member of the HSPA (HSP70) family of heat-shock proteins, encoded by the gene originally described as testis-specific. Recently, it has been reported that HSPA2 can be also expressed in human somatic tissues in a cell-type specific manner. HSPA2 is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. HSPA2 is involved in sperm maturity, function and fertility. Aberrant expression of HSPA2 in testes has been connected with male infertility. Recently, HSPA2 has attracted increased interest due to its possible involvement in carcinogenesis of non-testicular tissues. This antibody well recognized the endogenous HSPA4 protein in testis and multiple cell lines. (21373891)
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Anti-BAP28 Rabbit Polyclonal Antibody

Catalog Number: (103286-358)
Supplier: Novus Biologicals
Description: The BAP28 Antibody from Novus Biologicals is a rabbit polyclonal antibody to BAP28. This antibody reacts with human. The BAP28 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Image Unavailable-102992-738

LDK378 ≥95%

Supplier: Adipogen
Description: LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.

Product Image-95046-108

Anti-HSP110 Rabbit Polyclonal Antibody

Catalog Number: (95046-108)
Supplier: Enzo Life Sciences
Description: Hsp 110 belongs to a family of large stress proteins known as the Hsp110/SSE family, the mostly overlooked relatives of the well studied Hsp70 family. Members of this group, while significantly larger and containing sequences not present in the Hsp70 family, share 30-33% amino acid identity with members of the Hsp70 family, mostly in the conserved ATP-binding domain. Presently, all identified members of the Hsp70-like sequences belong to either the Hsp70 family or the Hsp110/SSE family. Hsp110 appears to be a normal constituent of mammalian cells with highest expression in the brain, and its induction by heat shock strongly correlates with cellular thermotolerance. Hsp110 may contribute to RNA stability, and its capacity to bind peptide has made Hsp110 a promising immunoadjuvant in anti-tumor vaccine development.
Image Unavailable-103271-150

Anti-HspB11 Rabbit Polyclonal Antibody

Catalog Number: (103271-150)
Supplier: Novus Biologicals
Description: The HspB11 Antibody from Novus Biologicals is a rabbit polyclonal antibody to HspB11. This antibody reacts with human. The HspB11 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Product Image-75793-426

Anti-CLU Rabbit Polyclonal Antibody

Catalog Number: (75793-426)
Supplier: Prosci
Description: Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
Image Unavailable-103409-916

Anti-AHSA1 Mouse Monoclonal Antibody [clone: 1D2]

Catalog Number: (103409-916)
Supplier: Novus Biologicals
Description: The AHSA1 Antibody (1D2) from Novus Biologicals is a mouse monoclonal antibody to AHSA1. This antibody reacts with human. The AHSA1 Antibody (1D2) has been validated for the following applications: Western Blot, Immunohistochemistry.
Image Unavailable-103281-044

Anti-HEATR5B Rabbit Polyclonal Antibody

Catalog Number: (103281-044)
Supplier: Novus Biologicals
Description: The HEATR5B Antibody from Novus Biologicals is a rabbit polyclonal antibody to HEATR5B. This antibody reacts with human. The HEATR5B Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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