You Searched For: Heat+Block

Supplier: GE Healthcare - HyClone

Description: HyClone Characterized Fetal Bovine Serum, Canadian origin, uses "True Pool" processing technology to ensure consistency in the quality of serum.

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Supplier: HPK Industries

Description: An extremely smooth outer fabric surface lowers particle cling and build-up in cleanroom applications

Catalog Number: (10260-160)

Supplier: Bioss

Description: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.

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Catalog Number: (75793-582)

Supplier: Prosci

Description: Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.

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Catalog Number: (76171-842)

Supplier: Boster Biological Technology

Description: Rabbit IgG polyclonal antibody for HSF2 detection. Tested with WB, Direct ELISA in Human;Mouse;Rat.

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Catalog Number: (76201-850)

Supplier: Enzo Life Sciences

Description: Recommended Applications: IHC, ISH (in situ hybridization)

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Catalog Number: (76397-904)

Supplier: Thermo Fisher Scientific

Description: The Nalgene™ multi-tiered portfolio provides bioproduction facilities with a variety of high-quality, sterile storage and transport solutions. Choose the appropriate product necessary to suit any application, through the step-down process and into the cleanroom.

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Supplier: Arlington Scientific

Description: A non-mammalian blocking reagent supplied in PBS for diagnostic systems involving membrane or other solid phase material.

Catalog Number: (75818-198)

Supplier: Azure Biosystems

Description: Azure Chemi Blot Blocking Buffer, Ready-to-use block that enhances chemiluminescent signal, for use with chemiluminescent Western blots to enhance signal and lower background. Size: 500mL

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Supplier: Excel Scientific

Description: AlumaSeal provides a secure seal for well plates to minimize evaporation, reduce cross-contamination and prevent spillage. The 38 µm thick adhesive provides a better sealing and evaporation control on PCR plates with narrow or irregular sealing surfaces.

Catalog Number: (10746-986)

Supplier: Thermco

Description: These high precision liquid-in-glass mercury thermometers are hand blown, which bear graduations, numbers and letters etched into the glass and filled with and inert gas above the mercury column

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Catalog Number: (77440-670)

Supplier: Bioss

Description: Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH1 (dynein heavy chain 1, axonemal), also known as heat shock regulated protein 1 or ciliary dynein heavy chain 1, is a 4,330 amino acid protein consisting of at least two heavy chains and several intermediate and light chains. Mutations in the gene encoding DNAH1 may be a cause of primary ciliary dyskinesia, also known as Kartagener Syndrome, which is characterized by chronic recurrent respiratory infections due to defective cilia action in the respiratory tract. There are three isoforms of DNAH1 that exist as a result of alternative splicing events.

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Catalog Number: (10371-696)

Supplier: Bioss

Description: Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).

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Catalog Number: (10800-390)

Supplier: Rockland Immunochemical

Description: Blocking Buffer Sampler Kit for ELISA, immunoassays, and western blot

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Catalog Number: (75793-608)

Supplier: Prosci

Description: Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.

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Supplier: Biotium

Description: This antibody recognizes a 24-27 kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced p29 and 24K protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.