You Searched For: Heat+Block

Catalog Number: (IC16009801)

Supplier: MP Biomedicals

Description: Deoxyribonucleic acid is a polynucleotide . It is an essential component of chromosomes in cell nuclei. It is the carrier of genetic material. It contains information in chemical code to direct the development of the cell according to its inheritance. The purine and pyrimidine bases of the nucleosides are primarily adenine, guanine, cytosine and thymine. The sugar is D-2-deoxyribose.

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Supplier: Adipogen

Description: Multipotent flavonoid antioxidant. Potent free radical scavenger. Neuroprotective. Anticancer compound with chemosensitizing activity. Cell cycle arrest, apoptosis and autophagy inducer. Proteasome inhibitor. Pleiotropic kinase inhibitor, including tyrosine protein kinase (Trk), mitochondrial ATPase, cAMP- and cGMP-phosphodiesterases, PI3-kinase activity, phospholipase A2 and protein kinase C (PKC). DNA topoisomerases inhibitor. SIRT1 activator. Heat shock proteins inhibitor. Reversible fatty acid synthase inhibitor. Antithrombotic, antihistaminic and anti-inflammatory agent. Monoamine oxidase inhibitor. Vasodilatory compound. anti-diabetic compound.

Catalog Number: (10282-226)

Supplier: Bioss

Description: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. [provided by RefSeq, Jul 2008].

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Catalog Number: (490012-374)

Supplier: Bel-Art Products

Description: Safe, non-slip protection against very hot or cold surfaces.

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Catalog Number: (470190-698)

Supplier: VWR

Description: Engage Students in a Hands-On Density Activity

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Supplier: Thermo Fisher Scientific

Description: Maximize valuable bench space with Thermo Scientific's compact and lightweight Dry Baths/Block Heaters, available with a variety of block size combinations for maximum sample versatility

Catalog Number: (76081-482)

Supplier: Bioss

Description: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.

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Catalog Number: (63041-040)

Supplier: Excelta

Description: This thick and medium pointed tweezer is excellent for general assembly.

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Catalog Number: (89522-662)

Supplier: Magid Glove

Description: The Magid® CutMaster® Machine Knit 100% Para-aramid® Protective Sleeves with Elastic Thumb Strap offer exceptional cut, puncture, abrasion, heat and flame resistance.

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Catalog Number: (TWTX758B)

Supplier: Texwipe

Description: The Micro Alpha® Swab, with its micro-sized tip, is excellent for cleaning very small grooved, slotted, and recessed areas as well as crevices and holes

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Supplier: Yamato Scientific

Description: Glassware Drying Ovens featuring a large window for easy observation.

Supplier: GE Healthcare - HyClone

Description: HyClone™ standard cell culture grade FBS is filtered through three sequential 100 µm (0,1 µm) pore-size rated filters.

Supplier: Ergomat

Description: The ERGOMAT® Hygiene is a cone profile ergonomic mat that is well suited for use in critical environments requiring daily caustic sanitation.

Catalog Number: (10371-718)

Supplier: Bioss

Description: Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).

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Catalog Number: (10082-304)

Supplier: Proteintech

Description: Archain 1 (ARCN1), also known as delta-COP, is a subunit of the coat protein I (COPI) complex, which comprises one of the protein coats that mediate vesicle budding from the membrane. Protein sequences of ARCN1 are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. The gene of ARCN1 has been identified in chromosome band 11q23.3, and sequencing of cDNAs suggests that at least two forms of mRNA with alternative 5' ends are present.

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Catalog Number: (10364-038)

Supplier: Bioss

Description: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4(HSF4) (By similarity). Highest levels within the nervous system, expressed in different tissues, mostly in intestine, placenta and lung. Increased expression during development. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain.

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