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Supplier: VWR International
Description: Deuterium Labeled Compounds. These high-quality products are used as solvents in NMR spectroscopy, R&D, tracers, and building blocks in pharmaceutical ingredients, as well as for the synthesis of organic light-emitting diodes (OLED).

SDS

Supplier: Wards
Description: Ideal for drying applications in microwave and ovens.

Catalog Number: (10110-140)
Supplier: Prosci
Description: Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand.Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-11 U26424.1 1-11 12-2826 BC010640.2 1-2815


Catalog Number: (10764-484)
Supplier: Prosci
Description: The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein. CD24 is known as the Heat Stable Antigen (HAS or HsAG) and is found on epithelial cells, thymocytes, monocytes, erythrocytes, granulocytes, dendritic cells and lymphocytes to the exclusion of NK cells. It is useful in delineating the stages of lymphocyte development and is involved in the costimulation of CD4+ T cells by B cells. CD62P (P-Selectin) is the reported ligand of CD24.


Supplier: American 3B Scientific
Description: Basic apparatus for providing contact, power supply and support to a germanium crystal on a circuit board in experiments on the Hall effect or on conductivity. Includes an integrated, adjustable constant current source to provide the current through the sample, a measuring amplifier with offset compensation for Hall voltages and heating to raise the crystal to as high as 170 °C, also featuring temperature regulation and a switchable display showing Hall voltage, sample current, sample voltage or temperature.

Catalog Number: (77438-268)
Supplier: Bioss
Description: Reactive oxygen species (ROS) are highly reactive molecules that are a normal consequence of aerobic metabolism. Cellular ROS damage can induce apoptosis and spontaneous mutagenesis. Oxr1 (Oxidation resistance protein 1) is a 758 amino acid mitochondrial protein that is most likely involved in protection from oxidative damage. Oxr1 is highly conserved from yeast to humans and is specific to eukaryotes.Induced by heat and oxidative stress, the carboxyl-terminal half of Oxr1 is required for its function. Upregulation of superoxide dismutase and catalase was observed in developing drosophila mutants that lacked the gene encoding Oxr1, suggesting that oxidative stress may trigger compensatory protein expression. There are four isoforms of Oxr1 that are produced as a result of alternative splicing events.


Supplier: Ward's
Description: Accessories for Digital Dry Bath Block Heaters

Supplier: Boekel
Description: Boekel scientific's dry block heaters are advanced, configurable and easy-to-use.

Catalog Number: (10086-496)
Supplier: Proteintech
Description: SCYE1(small inducible cytokine subfamily E, member 1) is also named as EMAP2, AIMP1. The human cDNA encodes a 312-amino acid polypeptide that the predicted 34-kD precursor can be cleaved to produce an active 20-kD product. SCYE1 is secreted as a result of various stimuli, including TNF-α, heat shock, and hypoxia, and that it acts as a multifunctional cytokine on both endothelial and immune cells. Defects in AIMP1 are the cause of leukodystrophy hypomyelinating type 3 (HLD3). It has 2 isoforms produced by alternative splicing and the protein can exsit as a dimer.


Supplier: VWR International
Description: Deuterium Labeled Compounds. These high-quality products are used as solvents in NMR spectroscopy, R&D, tracers, and building blocks in pharmaceutical ingredients, as well as for the synthesis of organic light-emitting diodes (OLED).

SDS

Catalog Number: (10364-032)
Supplier: Bioss
Description: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4(HSF4) (By similarity). Highest levels within the nervous system, expressed in different tissues, mostly in intestine, placenta and lung. Increased expression during development. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain.


Supplier: HPK Industries
Description: For contamination control in the cleanroom

Catalog Number: (89290-968)
Supplier: Genetex
Description: Rabbit polyclonal antibody to HSP20


Catalog Number: (102514-844)
Supplier: Adipogen
Description: Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.

Small Business Enterprise


Catalog Number: (89304-334)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to HSF1 (Phospho Ser307)


Catalog Number: (10408-928)
Supplier: Bioss
Description: Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes and the endoplasmic reticulum.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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