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Catalog Number: (77438-106)
Supplier: Bioss
Description: Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.


Catalog Number: (103284-936)
Supplier: Novus Biologicals
Description: The PRPF40B Antibody from Novus Biologicals is a rabbit polyclonal antibody to PRPF40B. This antibody reacts with human. The PRPF40B Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.


Catalog Number: (470001-900)
Supplier: United Scientific Supplies
Description: These large and colorful DNA, mRNA, ribosome, tRNA, and amino acid models are visible anywhere in the classroom.


Catalog Number: (103259-016)
Supplier: Novus Biologicals
Description: The PRPF3 Antibody from Novus Biologicals is a rabbit polyclonal antibody to PRPF3. This antibody reacts with human. The PRPF3 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (10097-154)
Supplier: Proteintech
Description: WTAP, also named as KIAA0105 and hFL(2)D, is previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. It is a Pre-mRNA-splicing regulator protein. It is a regulatory subunit of the WMM N6-methyltransferase complex which plays a role in the efficiency of mRNA splicing and processing and mRNA stability. It is required for accumulation of METTL3 and METTL14 to nuclear speckle.


Catalog Number: (103259-012)
Supplier: Novus Biologicals
Description: The PRPF4 Antibody from Novus Biologicals is a rabbit polyclonal antibody to PRPF4. This antibody reacts with human, mouse, rat. The PRPF4 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (10108-098)
Supplier: Prosci
Description: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly (A) and poly (U) RNA sequences.


Catalog Number: (77436-856)
Supplier: Bioss
Description: The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.


Catalog Number: (10388-528)
Supplier: Bioss
Description: Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons; for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed.


Catalog Number: (101641-564)
Supplier: New England Biolabs (NEB)
Description: Release factors are involved in termination of protein translation by recognizing the stop codons in an mRNA sequence

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Catalog Number: (103260-766)
Supplier: Novus Biologicals
Description: The CWC22 Antibody from Novus Biologicals is a rabbit polyclonal antibody to CWC22. This antibody reacts with human. The CWC22 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (103258-740)
Supplier: Novus Biologicals
Description: The PRPF39 Antibody from Novus Biologicals is a rabbit polyclonal antibody to PRPF39. This antibody reacts with human, mouse, rat. The PRPF39 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (103284-938)
Supplier: Novus Biologicals
Description: The PRPF40B Antibody from Novus Biologicals is a rabbit polyclonal antibody to PRPF40B. This antibody reacts with human. The PRPF40B Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.


Catalog Number: (103285-346)
Supplier: Novus Biologicals
Description: The SCAF1 Antibody from Novus Biologicals is a rabbit polyclonal antibody to SCAF1. This antibody reacts with human. The SCAF1 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (76063-128)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000


Catalog Number: (76010-858)
Supplier: Prosci
Description: RBM42 binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA (By similarity).


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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