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Supplier: CUBE BIOTECH
Description: AASTYs (Acrylic acid-co-styrenes) - like AASTY 6-50 - are highly-alternating copolymers, well-suited for the generation of native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 6-50 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-50 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.

The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made using controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs.

Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022

Catalog Number: (TCG0250-25G)
Supplier: TCI America
Description: CAS Number: 3087-16-9 MDL Number: MFCD00012117 Molecular Formula: C27H26N2O7S2 Molecular Weight: 576.61 Form: Crystal Color: Deep Yellow Red

Catalog Number: (TS19010-0250)
Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: Acid green 50, pure


Supplier: DuPont
Description: ProShield® 50 garments are suitable for protection against non-hazardous particles, light liquid splash and aerosols in many industrial applications.

Supplier: VWR International
Description: Papanicolaou stains are used in conjunction with Hematoxylin nuclear stains in the diagnosis of malignant cytological diseases.
Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: Amberlite® CG-50 ion-exchange resin Type 1

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Supplier: DuPont
Description: ProShield® 50 garments are suitable for protection against non-hazardous particles, light liquid splash and aerosols in many industrial applications.

Supplier: CUBE BIOTECH
Description: AASTYs (Acrylic acid-co-styrenes) - like AASTY 11-50 - are highly-alternating copolymers, well-suited for the generation of native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 11-50 gets its name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-45 tend to be more aggressive, while heavier AASTYs, such as 11-50 show higher thermodynamic stability.

Every membrane protein solubilization needs to undergo a screening process in before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process, we offer a handy Screening Kit for AASTYs to test them all.

We recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022

Supplier: DuPont
Description: ProShield® 50 garments are suitable for protection against non-hazardous particles, light liquid splash and aerosols in many industrial applications.

Catalog Number: (15204-216)
Supplier: MilliporeSigma
Description: Cytoplasmic counterstain for Pap staining technique.

Supplier: DuPont
Description: ProShield® 50 garments are suitable for protection against non-hazardous particles, light liquid splash and aerosols in many industrial applications.

Catalog Number: (BJ492-4)
Supplier: Honeywell Research Chemicals
Description: LabReady™ Solvent Blends


Supplier: Electron Microscopy Sciences
Description: Papanicolaou Stain Solution, EA-50 (EA Counterstain).

Minority or Woman-Owned Business Enterprise

Catalog Number: (89370-816)
Supplier: Epredia
Description: Clearly differentiate cellular components with pink, green and blue-green hues utilizing Epredia™ Shandon™ EA-50 Stain.

SDS


Catalog Number: (13452-326)
Supplier: DuPont
Description: ProShield® 60 garments are suitable for protection against non-hazardous particles, light liquid splash and aerosols in many industrial applications.


Supplier: Epredia
Description: Control the color hues and intensities of your work with Epredia™ Papanicolaou EA Stain, useful for both gynecological and non-gynecological staining.

SDS

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

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  • State issued document with your organization's Federal Tax ID Number
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* Please note if your account is within the State of California two of these pieces of identification will be required.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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