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Image Unavailable-10351-750

Anti-FOXO3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10351-750)
Supplier: Bioss
Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Image Unavailable-10398-548

Anti-NOX4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10398-548)
Supplier: Bioss
Description: Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
Image Unavailable-76098-570

Anti-Rad51 Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Catalog Number: (76098-570)
Supplier: Bioss
Description: Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Image Unavailable-10394-188

Anti-cGMP Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10394-188)
Supplier: Bioss
Description: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
Product Image-62404-982

Corning® Culture Tubes

Catalog Number: (62404-982)
Supplier: Corning
Description: Optically clear PS.

Certificates Environmentally Preferable Product available on GSA Advantage®


Image Unavailable-700006-676

Tritolyl phosphate (mixture of isomers) ≥90%, Technical Grade

Supplier: Spectrum Chemicals
Description: Tritolyl Phosphate, Technical, also known as tri-o-cresyl phosphate, can be used as a plasticizer and as a gasoline additive.

Certificates Small Business Enterprise

Image Unavailable-102981-772

Anti-CD155 Monoclonal Antibody [clone: ANC2B2]

Catalog Number: (102981-772)
Supplier: Adipogen
Description: Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.
Image Unavailable-102991-206

WSP1 ≥97% (by NMR)

Supplier: Adipogen
Description: Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.

Image Unavailable-10395-668

Anti-PPARA Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10395-668)
Supplier: Bioss
Description: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Product Image-PI51140

Water for LC-MS, Pierce™

Catalog Number: (PI51140)
Supplier: Thermo Fisher Scientific Chemicals Inc.
Description: Thermo Scientific Pierce Water, LC-MS Grade is an ultrapure, LC-MS grade preparation with low UV-absorptivity that makes it suitable and reliable for use in HPLC and mass spectrometry applications.

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Image Unavailable-102980-446

Human NAPRTase (from E. coli)

Catalog Number: (102980-446)
Supplier: Adipogen
Description: Human nicotinate phosphoribosyltransferase (NAPRTase) is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process
Image Unavailable-10320-938

Anti-TRP1 Rabbit Polyclonal Antibody (HRP)

Catalog Number: (10320-938)
Supplier: Bioss
Description: Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
Image Unavailable-10320-642

Anti-FOXO3A Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10320-642)
Supplier: Bioss
Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Image Unavailable-10320-644

Anti-FOXO3A Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10320-644)
Supplier: Bioss
Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Image Unavailable-10082-758

Anti-ALDH2 Rabbit Polyclonal Antibody

Catalog Number: (10082-758)
Supplier: Proteintech
Description: Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.
Image Unavailable-101171-002

(±)-α-Lipoic acid ≥98.0% (dry basis)

Supplier: Thermo Fisher Scientific Chemicals Inc.
Description: 100 gm

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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